Stereochemistry of Quinolizidines. II. Carbon-13 Magnetic Resonance Spectra of N-Methylquinolizidinium Ions
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概要
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The carbon magnetic resonance spectra of trans-(I) and cis-N-methylquinolizidinium ion (II) were examined in relation to the stereochemistry of these compounds. Ring inversion of the cis-N-methylquinolizidinium ion was observed in variable temperature experiments and results afforded ΔGc^≠=13.7 kcal/mole. The observed carbon chemical shift difference between I and II was compared with that estimated empirically, and shown to be a measure of the stereochemical difference between the trans-and cis-forms of the quinolizidine nucleus.
- 公益社団法人日本薬学会の論文
- 1977-05-25
著者
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佐々木 喜男
Faculty of Pharmaceutical Sciences, Osaka University
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佐々木 喜男
Faculty Of Pharmaceutical Sciences Osaka University
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高尾 楢雄
Kobe Women's College of Pharmacy
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高尾 楢雄
Kobe Women's College Of Pharmacy
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