Modeling of Agitation Fluidized Bed Granulation by Random Coalescence Model
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概要
- 論文の詳細を見る
Modeling of agitation fluidized bed granulation was conducted using a proposed random coalescence model, in which adhesion of two colliding particls was judged by the coherent strength of a liquid bridge formed between the particles and the separation force caused mainly by agitator rotation. Properties of coherent strangth and water absorbing characteristics of the starting materials, which were very important to determine granule growth, were also teken into consideration. Granule growth in various powder samples with different properties were simulated and the effects of moisture content and agitator rotational speed on this growth were numerically investigeted. The simulated results were in good agreement with the actual granulation data, and granule growth in various powder samples and operating conditions could be simulated with high accuracy. The mechanism of agitation fluidized bed granulation was also elucidated by the proposed model.
- 公益社団法人日本薬学会の論文
- 1996-07-15
著者
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Watano S
Osaka Prefecture University
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Watano Satoru
Department Of Chemical Engineering Osaka Prefecture University
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Watano Satoru
Department Of Chemical Engineering Graduate School Of Engineering Osaka Prefecture University
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YASUTOMO Teruhito
Taiho Pharmaceutical Co., Ltd.
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MIYANAMI KEI
Department of Chemical Engineering, Osaka Prefecture University
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Miyanami K
Department Of Chemical Engineering Osaka Prefecture University
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Miyanami Kei
Department Of Chemical Engineering Osaka Prefecture University
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UCHIGAMI Masafumi
Department of Chemical Engineering, University of Osaka Prefecture
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Uchigami Masafumi
Department Of Chemical Engineering University Of Osaka Prefecture
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Yasutomo Teruhito
Control Department Taiho Pharmaceutical Co. Ltd.
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