Preparation of Core Particles for Aqueous Film Coating Using Agitation Fluidized Bed
スポンサーリンク
概要
- 論文の詳細を見る
Core particles used for aqueous film coating were prepared by agitation fluidized bed granulation, and effect of the damping speed on the granule properties of mass median diameter, geometric standard deviation, apparent density, yield friability and specific surface area were investigated. Film coating by an aqueous acylic copolymer (Eudragit NE-30D) was carried out using the core particles granulated under three levels of damping speeds, and the drug release properties of each coated product were identified. Relationship between properties of core particles and the release properties were clarified and the optimal granulation conditions to make optimal core particles for film coating were determined.
- 公益社団法人日本薬学会の論文
- 1997-12-15
著者
-
Watano Satoru
Department Of Chemical Engineering Graduate School Of Engineering Osaka Prefecture University
-
Miyanami Kei
Department Of Chemical Engineering Osaka Prefecture University
-
ANDO Kengo
Department of Chemical Engineering, Osaka Prefecture University
-
II Yoshinori
One Pharmaceutical Co., Ltd.,
-
SASATANI Seiei
One Pharmaceutical Co., Ltd.,
-
Ando Kengo
Department Of Chemical Engineering Osaka Prefecture University
-
Ii Yoshinori
One Pharmaceutical Co. Ltd.
-
Sasatani Seiei
One Pharmaceutical Co. Ltd.
関連論文
- Improvement of Dissolution Property of Poorly Water-Soluble Drug by Supercritical Freeze Granulation
- Improvement of Dissolution Property of Poorly Water-Soluble Drug by Novel Dry Coating Method Using Planetary Ball Mill
- Removal of Fine Powders from Film Surface. I. Effect of Electrostatic Force on the Removal Efficiency
- Optimization and validation of an image processing system in fluidized bed granulation
- IR absorption characteristics of an IR moisture sensor and mechanism of water transfer in fluidized bed granulation
- Control Granule Growth in Fluidized Bed Granulation by an Image Processing System
- Measurement of Moisture Content by IR Sensor in Fluidized Bed Granulation. Effects of Operating Variables on the Relationship between Granule Moisture Content and Absorbance of IR Spectra
- Control of moisture content by adaptive fuzzy control in agitation fluidized bed granulation
- APPLICATION OF FUZZY LOGIC TO MOISTURE CONTROL IN FLUIDIZED BED GRANULATION
- Heat Transfer and the Mechanism of Drying in Agitation Fluidized Bed
- Development of a Novel Compression Tester and Rheo-Mechanical Properties of Wet-Mass Powder.II : Effect of Moisture Content on the Rheo-Mechanical Properties
- Development of a Novel Compression Tester and Rheo-Mechanical Properties of Wet-Mass Powder.I : Effect of Kneading Time on the Rheo-Mechanical Properties
- Novel mechanochemical process for synthesis of magnetite nanoparticles using coprecipitation method
- Granulation of Core Particles Suitable for Film Coating by Agitation Fluidized Bed III : Effect of Scale, Agitator Rotational Speed and Blade Shape on Granule Properties and Development of a High Accuracy Scale-Up Theory
- Granulation of Core Particles Suitable for Film Coating by Agitation Fluidized Bed II. : A Proposal of a Rapid Dissolution Test for Evaluation of Bitter Taste of Ibuprofen
- Granulation of Core Particles Suitable for Film Coating by Agitation Fluidized Bed I. Optimum Formulation for Core Particles and Development of a Novel Friability Test Method
- Surface Modification of Food Fiber by Dry Particle Coating
- Numerical Simulation of Film Coating Process in a Novel Rotating Fluidized Bed
- Scale-Up of Agitation Fluidized Bed Granulation by Neural Network
- Scale-Up of Agitation Fluidized Bed Granulation. V. Effect of Moisture Content on Scale-Up Characteristics
- Quantitative evaluation of kneading and extrusion processes by pressure transmission characteristics of wet kneaded masses
- Modeling of Agitation Fluidized Bed Granulation by Random Coalescence Model
- Heat Transfer and Granule Growth Rate in Fluidized Bed Granulation
- Mathematical Model in the Kinetics of Agitation Fluidized Bed Granulation. Effects of MOisture Content, Damping Speed and Operation Time on Granule Growth Rate
- COMPUTER SIMULATION OF AGITATION FLUIDIZED BED GRANULATION BY A TWO-DIMENSIONAL RANDOM ADDITION MODEL
- COMPUTER SIMULATION OF FLUIDIZED BED GRANULATION BY A TWO-DIMENSIONAL RANDOM COALESCENCE MODEL
- Drying of Granules in Agitation Fluidized Bed
- Development of a novel particle size control system for hammer milling
- Determination of Optimal Formulation for Extrusion Granulation by Compression Test of Wet Kneaded Mass
- Quantitative Analysis of Water Dispersion Conditions and Pressure Transmission Characteristics of a Wet Kneaded Mass
- A method for process monitoring and determination of operational end-point by frequency analysis of power consumption in agitation granulation
- Removal of Fine Powders from Film Surface. II. Effect of Operating Parameters on the Removal Efficiency
- Scale-up methodology for tumbling ball mill based on impact energy of grinding balls using discrete element analysis
- Continuous Monitoring and Mechanism of Electrostatic Charge of Powder in Fluidized Bed Process
- Kneading and dispersion of positive electrode materials in a lithium ion secondary battery for high-density film
- Effect of Spray Mist Size on the Properties of Granules Prepared by Agitation Fluidized Bed Coating
- Preparation of Core Particles for Aqueous Film Coating Using Agitation Fluidized Bed
- Prediction of Granule Physical Property by a Novel Compression Energy of Wet Powder
- Development of a Novel Granular Detergent by Inorganic Solution Binder
- Development of a Novel Granular Detergent with an Interspersion Particle Comprising an Anionic Surfactant and a Polymeric Polycarboxalate
- Development of a High Active Surfactant and High Soluble Granular Detergent by Secondary Alkyl Sulfate
- Monitoring and Scale-Up of Static Electrification during Solid-Liquid Mixing
- Rheological Analysis and Quantitative Evaluation of Wet Kneaded Wax Matrix
- Measurement of Physical Strength of Pharmaceutical Extruded Pellets
- Development of a Novel Tablet Machine for a Tiny Amount of Powder and Evaluation of Capping Tendency
- In-Die Evaluation of Capping Tendency of Pharmaceutical Tablets Using Force-Displacement Curve and Stress Relaxation Parameter
- My impression of APT2000
- GAS HOLDUP AND PRESSURE DROP IN A MULTISTAGE VIBRATING DISK COLUMN WITH COCURRENT GAS-LIOUID FLOW
- Control of moisture content in fluidized bed granulation by neural network.
- A model for extractive coal liquefaction. Modeling and simulation of NenKen process without coal particle disintegration.:MODELING AND SIMULATION OF NENKEN PROCESS WITHOUT COAL PARTICLE DISINTEGRATION
- APPLICABILITY OF DISPERSION MODEL TO A PACKED BED REACTOR WITH AN IRREVERSIBLE CHEMICAL REACTION OF THE 2ND ORDER
- MASS TRANSFER IN A MULTISTAGE VIBRATING DISK COLUMN WITH COCURRENT GAS-LIQUID FLOW
- THE EFFECT OF THE WAVE FORM OF DISK VIBRATION ON MASS TRANSFER IN A MULTISTAGE VIBRATING DISK COLUMN WITH COUNTERCURRENT LIQUID-LIQUID FLOW
- LIQUID-PHASE MIXING IN A MULTISTAGE VIBRATING-DISK COLUMN WITH CONCURRENT GAS-LIQUID FLOW
- TRACER INTRODUCTION BY ELECTROLYSIS