Mathematical Model in the Kinetics of Agitation Fluidized Bed Granulation. Effects of MOisture Content, Damping Speed and Operation Time on Granule Growth Rate
スポンサーリンク
概要
- 論文の詳細を見る
A population balance equation, in which moisture content was taken into consideration for the coalescence probability of two colliding granules, was proposed to investigate the kinetics of granule growth in agitation fluidized bed granulation. The effects of operating variables such as moisture content, damping speed and operation time on the granule growth and its rate were numerically examined. It was found that the theoretical results intrinsically revealed these effects on granule size, size distribution and granule growth rate. The theory also showed good agreement with the experimental granulation data for pharmaceutical powders. As a result, the granule growth mechanism in agitation fluidized bed granulation was elucidated in detail.
- 公益社団法人日本薬学会の論文
- 1996-02-15
著者
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Watano S
Osaka Prefecture University
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Watano Satoru
Department Of Chemical Engineering Osaka Prefecture University
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Watano Satoru
Department Of Chemical Engineering Graduate School Of Engineering Osaka Prefecture University
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MIYANAMI KEI
Department of Chemical Engineering, Osaka Prefecture University
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Morikawa Takashi
Department Of Chemical Engineering University Of Osaka Prefecture
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Miyanami K
Department Of Chemical Engineering Osaka Prefecture University
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Miyanami Kei
Department Of Chemical Engineering Osaka Prefecture University
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Morikawa Takashi
Department Of Biochemistry & Immunochemistry Research Division Panapharm Laboratories Co. Ltd.
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