Effect of Spray Mist Size on the Properties of Granules Prepared by Agitation Fluidized Bed Coating
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概要
- 論文の詳細を見る
In this contribution, an organic solvent-based enteric coating was made using an agitation fluidized bed. Core spherical particles containing an aqueous pigment were coated with an enteric methacrylate-methyl methacrylate copolymer dissolved in an ethanol solution using an agitation fluidized bed under various spray mist sizes. Physical properties of coated granules such as the drug release properties, the specific surface are and the coating efficiency were investigated. The effect of spray mist size on the properties of coated granules was investigated and the film forming mechanism in agitation fluidized bed coating was discussed. The optimum operating conditions were also determined.
- 公益社団法人日本薬学会の論文
- 1996-11-15
著者
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Watano Satoru
Department Of Chemical Engineering Graduate School Of Engineering Osaka Prefecture University
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Miyanami Kei
Department Of Chemical Engineering Osaka Prefecture University
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Yamamoto Atsuko
Department Of Chemical Engineering Osaka Prefecture University
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