Platinum and Palladium Complexes Containing Ethylenediamine Derivatives as Carrier Ligands and Their Antitumor Activity

スポンサーリンク

概要

• 論文の詳細を見る

• We prepared new antitumor active platinum complexes containign N, N'-bis(2-chloroethyl)ethylenediamine (ClEn) as an alkylating carrier ligand in order to obtain increased antitumor effects. Some of the platinum complexes synthesized showed enhanced antitumor activity. However, palladium(II) complexes containing ClEn were inactive against L1210 and P388.

• 公益社団法人日本薬学会の論文
• 1994-03-15

著者

• 田代 田鶴子

  Division of Experimental Chemotherapy Cancer Chemotherapy Center

• 野路 雅英

  Faculty of Pharmaceutical Sciences, Nagoya City University

• LEE Keun-Im

  Department of Pharmacy, Graduate School, Sookmyung Women's University

• 野路 雅英

  Faculty Of Pharmaceutical Sciences Nagoya City University

• Lee Keun-im

  Department Of Pharmacy Graduate School Sookmyung Women's University

• 野路 雅英

  名古屋市大 薬

• Lee Keun-Im

  Department of Manufacturing Pharmacy, College of Pharmacy, Sookmyung Women's University

関連論文

• Synthesis and Antitumor Activity of Fused Quinoline Derivatives. III. Novel N-Glycosylamino-indolo[3,2-b]quinolines
• Synthesis and Antitumor Activity of Fused Quinoline Derivatives
• THE SYNTHESIS AND ANTITUMOR ACTIVITIES OF TROPOLONE AND 8-HYDROXYQUINOLINE DERIVATIVES
• Antineoplastic Activity of Platinum Complexes of trans-(dl)-1,2-Cyclopentanediamine
• 1R,2R-シクロヘキサンジアミンを配位子にもつ四価および二価白金錯体の細胞毒性(発表論文抄録(1993))
• Cytotoxicity of Platinum(IV) and Platinum(II) Complexes Containing 1R, 2R-Cyclohexanediamine as a Ligand
• Purification and Characterization of Mouse α_1-Acid Glycoprotein and Its Possible Role in the Antitumor Activity of Some Lichin Polysaccharides
• Syntheses and Antitumor Activities of 1R,2R-Cyclohexanediamine Pt(II) Complexes Containing Dicarboxylates(Medicinal Chemistry,Chemical)
• Cyanine Dyes, New Potent Antitumor Agents
• 白金ホスフィン錯体のラマンスペクトル
• The Crystal Structure and Absolute Configuration of the Antitumor Platinum Complex tran(OH)-Pt(OH)_2(Malonato)(1R, 2R, -Cyclohexanediamine)
• Studies on Synthesis, Structure, and Antitumor Activity of Pt(II) Complexes Containing 1,2-Diamino-1,2-dideoxy-D-glucitol
• The Measurement of cis-Platin and trans-Platin by Graphite Atomic Absorption Spectrophotometry
• Magnetic Circular Dichroic Spectra of Various Adducts of Co (II)-Bovine Carbonic Anhydrase
• 1,2-シクロヘキサンジアミンおよび2-(アミノメチル)シクロヘキシルアミン異性体の白金(4)錯体の制がん性と性質 (生体関連物質と配位化学) -- (生理・薬理活性)
• Platinum and Palladium Complexes Containing Ethylenediamine Derivatives as Carrier Ligands and Their Antitumor Activity
• Synthesis and Antitumor Activity of Pt (II) Complexes containing 2,3-Diaminopropanol Isomers
• Synthesis of Pt(II) Complexes Containing D-Glucuronate, D-Gluconate, or Their Acetyl Derivatives and Evaluation of Antitumor Activity against Murine Leukemia L1210
• Synthesis and Antitumor Activity of Riboflavin and Flavin Mononucleotide Pt(II) Complexes
• Antitumor Activity of Pt(II) Complexes Containing Diaminocarboxylates and Their Ester Derivatives
• Platinum Complexes of Diaminocarboxylates and Their Ethyl Ester Derivatives : Antitumor Activity and Interaction with Deoxyribonucleic Acid
• Studies on the Mixed-Ligand Complexes. III. Mixed-Ligand Complexes between Alloxan and Glycine with Bivalent Metals
• Studies on the Mixed-Ligand Complexes. II. Synthesis of the Mixed-Ligand Complexes between 8-Hydroxyquinoline-5-sulfonic Acid and L-Histidine with Metals
• 金属錯体化学からみた発癌と制癌
• 癌と白金錯体--第3世代抗癌性白金錯体の開発 (微量金属の生体作用--金属イオンの生理機能と薬理作用解明をめざして) -- (疾患と微量金属)
• 制がん作用をもった白金錯体 (金属イオンの生物活性--生物無機化学の新しい流れ)
• Preparation of Platinum (II) Complexes of Diamine Isomers [PtX (1,3-Diamine)] (X=Cl_2,SO_4,(NO_3)_2,Oxalato, D-Glucuronato, and D-Gluconato) and Determination of Their Antitumor Activity against Leukemia L1210
• Antitumor Activity of Platinum(2) Complexes of 1,2-Diamino-Cyclohexane Isomers
• Synthesis of Platinum (II) Complexes of 4-Substituted o-Phenylenediamine Derivatives and Determination of Their Antitumor Activity
• エチレジアミンおよびジカルボン酸イオンを含む混合配位子銅(2)錯体の分光光度法による平衡定数の測定
• The synthesis of polymeric catalyst using ion exchange resin and its application for esterification.

もっと見る 閉じる

スポンサーリンク