The Measurement of cis-Platin and trans-Platin by Graphite Atomic Absorption Spectrophotometry

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概要

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• In order to determine a micro amount of cis- and trans-platin (cis- and trans-diamminedichloroplatinum(II)) separately, we have utilized the trans effect of SCN^-.cis-Platin reacted with potassium thiocyanate to give anionic [Pt(SCN)_4]^<2-> which was extracted into nitroethane as an ion pair with zephiramine. On the other hand, trans-platin gave neutral trans-[Pt(SCN)_2(NH_3)_2] under the same conditions, which was not extracted into nitroethane. Therefore, it is possible to determine cis- and trans-platin, separately, by the solvent extraction method. In the determination of the mixture of cis- and trans-platin (4.00×10^<-6> and 2.67×10^<-6>M, respectively), the recovery of each platinum complex was 94±4 and 101±10% for cis- and trans-platin, respectively.

• 公益社団法人日本薬学会の論文
• 1991-05-25

著者

• 喜谷 喜徳

  Faculty of Pharmaceutical Sciences Nagoya City University

• 野路 雅英

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 廣瀬 順造

  Department Of Food Science And Technology Faculty Of Engineering Fukuyama University

• 櫛田 郁雄

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 櫛田 郁雄

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 田中 亜弓

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 廣瀬 順造

  Faculty of Engineering, Department of Food Science and Technology, Fukuyama University

• 酒井 忠雄

  College of Liberal Arts, Asahi University

• FENGZE Zhao

  Department of Pharmacy, Yanbian Medical College

• 喜谷 喜徳

  名古屋市立大学薬学部

• 野路 雅英

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 酒井 忠雄

  College Of Liberal Arts Asahi University

• 酒井 忠雄

  Department Of Chemistry Gifu College Of Dentistry

• Fengze Zhao

  Department Of Pharmacy Yanbian Medical College

• 野路 雅英

  名古屋市大 薬

• 田中 亜弓

  Faculty Of Pharmaceutical Sciences Nagoya City University

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