Synthesis of Platinum (II) Complexes of 4-Substituted o-Phenylenediamine Derivatives and Determination of Their Antitumor Activity
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概要
- 論文の詳細を見る
Pt (II) complexes of 4-substituted o-phenylenediamine (opda-R ; R=CH_3,OCH_3,H, Cl, COOH, NO_2,and SO_3H), PtX_2 (opda-R), were synthesized and tested for antitumor activity against P-388 leukemia. The infrared spectra of those complexes were analyzed to assign the Pt-N stretching vibrations on the basis of the halogeno trans effect and Hammett's σ values. The assigned Pt-N strectching vibrations were related to the antitumor activities of the opda-R Pt (II) complexes.
- 公益社団法人日本薬学会の論文
- 1979-11-25
著者
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喜谷 喜徳
Faculty of Pharmaceutical Sciences Nagoya City University
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浅野 陽一
Faculty Of Pharmaceutical Sciences Nagoya City University
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野路 雅英
Faculty Of Pharmaceutical Sciences Nagoya City University
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野路 雅英
名古屋市大 薬
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