IDENTIFICATION OF 27-NOR-3α, 7α, 12α-TRIHYDROXYCOPROSTAN-24-ONE APPARENTLY DERIVED FROM 3α, 7α, 12α-TRIHYDROXY-24-OXOCOPROSTANOIC ACID, A POSTULATED INTERMEDIATE OF BILE ACID BIOSYNTHESIS
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概要
- 論文の詳細を見る
Incubation of [27-^<13>C]-3α, 7α, 12α-trihydroxycoprost-24-en-26-oic acid with rat liver homogenate followed by ^<13>C-NMR analysis of the incubation product has resulted in the identification of[26-^<13>C]-27-nor-3α, 7α, 12α-trihydroxycoprostan-24-one, supporting the idea that the substrate has been metabolized into 3α, 7α, 12α-trihydroxy-24-oxocoprostan-26-oic acid CoA derivative.
- 社団法人日本薬学会の論文
- 1993-07-15
著者
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小林 典子
共立薬大
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森崎 益雄
共立薬大
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由利 正利
東工大・理
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小林 典子
Kyoritsu College of Pharmacy
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森崎 益雄
Kyoritsu College of Pharmacy
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由利 正利
Department of Chemistry, Tokyo Institute of Technology
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藤本 善徳
Department of Chemistry, Tokyo Institute of Technology
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原 典行
Department of Chemistry, Tokyo Institute of Technology
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徳元 真理絵
Department of Chemistry, Tokyo Institute of Technology
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藤本 善徳
東工大院理工
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藤本 善徳
Department Of Chemistry Tokyo Institute Of Technology
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徳元 真理絵
Department Of Chemistry Tokyo Institute Of Technology
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原 典行
東工大院理工
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原 典行
Department Of Chemistry Tokyo Institute Of Technology
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