ORBITAL DISTORTION ARISING FROM REMOTE SUBSTITUENTS NITRATION AND REDUCTION OF SPIRO[CYCLOPENTA-1,9'-FLUORENE]-2-ONES
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概要
- 論文の詳細を見る
Nitration of spiro[cyclopenta-1,9'-fluorene]-2-one with acetyl nitrate predominantly gave the 4-nitro derivative. In the reduction of substituted spiro[cyclopenta-1,9'-fluorene]-2-ones, the anti-alcohols were favored in all cases. Both anomalous distributions of the products can be interpreted in terms of interactions of the π orbitals of the aromatic and the carbonyl moieties. This example of stereoelectronic effects demonstrates intrinsic reciprocal distortion between sterically unbiased π frameworks of the molecule.
- 公益社団法人日本薬学会の論文
- 1991-08-25
著者
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首藤 紘一
Faculty of Pharmaceutical Sciences, University of Tokyo
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首藤 紘一
Facutly Of Pharmaceutical Sciences University Of Tokyo
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大和田 智彦
東大 薬
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大和田 智彦
Faculty of Pharmaceutical Sciences, University of Tokyo
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首藤 紘一
東京大・薬学
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大和田 智彦
Faculty Of Pharmaceutical Sciences University Of Tokyo
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