Structural Identification of a Modified Base in DNA covalently Bound with Mutagenic 3-Amino-1-methyl-5H-pyrido [4,3-b] indole

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概要

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• A mutagen, 3-amino-1-methyl-5H-pyrido [4,3-b] indole (Trp-P-2,1), was reacted with DNA in the presence of rat liver microsomes. One of the modified bases was identified as 3-(C^8-guanyl) amino-1-methyl-5H-pyrido [4,3-b] indole (2).

• 1979-04-25

著者

• 首藤 紘一

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 岡本 敏彦

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 橋本 祐一

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 首藤 紘一

  東京大・薬学

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