Studies on Balanites aegyptiaca Fruits, an Antidiabetic Egyptian Folk Medicine
スポンサーリンク
概要
- 論文の詳細を見る
An aqueous extract of mesocarps of the fruits of Balanites aegyptiaca exhibited a prominent antidiabetic activity by oral administraction in streptozotocin induced diabetic mice. From one of the active fractions of this extract, two new steroidal saponins were isolated, and their structures were determined as 26-O-β-D-glucopyranosyl-(25R)-furost-5-ene-3β, 22,26-triol 3-O-[α-L-rhamnopyranosyl-(1→2)]-[β-D-xylopyranosyl-(1→3)]-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside and its 22-methyl ether. In addition, two known saponins, 26-O-β-D-glucopyranosyl-(25R)-furost-5-ene-3β, 22,26-triol 3-O-(2,4-di-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside and its methyl ether were isolated and identified. It was revealed that the individual saponins did not show antidiabetic activity, while the recombination of these saponins resulted in significant activity. From an ethanolic extract of the epicarps, two known flavonol glycosides, isorhamnetin-3-O-robinobioside and isorhamnetin-3-O-rutinoside were isolated and identified.
- 社団法人日本薬学会の論文
- 1991-05-25
著者
-
田中 治
広島大
-
田中 治
Faculty Of Pharmaceutical Sciences University Of Tokyo:(present Address) Pharmaceutical Institute Sc
-
大谷 和弘
広島大・医
-
笠井 良次
広島大・医
-
KAMEL Mohamed
Pharmacognosy Department, Assiut University
-
大谷 和弘
Faculty of Pharmacy, Assiut, Egypt, Institute of Pharmaceutical Sciences, Hiroshima University, Scho
-
黒川 知則
Faculty of Pharmacy, Assiut, Egypt, Institute of Pharmaceutical Sciences, Hiroshima University, Scho
-
ASSAF Mahmoud
Pharmacognosy Department, Assiut Uiversity
-
EL-SHANAWANY Mohamed
Pharmacognosy Department, Assiut Uiversity
-
ALI Ahmed
Pharmacognosy Department, Assiut Uiversity
-
笠井 良次
Faculty of Pharmacy, Assiut, Egypt, Institute of Pharmaceutical Sciences, Hiroshima University, Scho
-
石橋 貞彦
Faculty of Pharmacy, Assiut, Egypt, Institute of Pharmaceutical Sciences, Hiroshima University, Scho
-
石橋 貞彦
広島大学医学部総合薬学科
-
Ali Ahmed
Pharmacognosy Department Assiut Uiversity
-
黒川 知則
広島大医・総合薬・生理化学
-
El-shanawany Mohamed
Pharmacognosy Department Assiut Uiversity
-
田中 治
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
-
Kamel Mohamed
Pharmacognosy Department Assiut University
-
Assaf Mahmoud
Pharmacognosy Department Assiut Uiversity
関連論文
- 土貝母サイクリックビステスモシドの溶解促進及び包接作用
- Saponins from Chinese Medicinal Plant, Hemsleya graciliflora (Cucurbitaceae)
- TUBEIMOSIDE I, A NEW CYCLIC BISDESMOSIDE FROM CHINESE CUCURBITACEOUS FOLX MEDICINE "TU BEI MU", A TUBER OF Bolbostemma paniculatum
- 98 中国産ウリ科生薬土貝母より得られる新サイクリックビスデスモサイドについて : 構造と溶解促進効果
- Tannins and Related Compounds. CXXII. New Dimeric, Trimeric and Tetrameric Ellagitannins, Lambertianins A-D, from Rubus lambertianus SERINGE
- Saponins from Vietnamese Ginseng, Panax vietnamensis HA et GRUSHV. Collected in Central Vietnam. I
- 56(P21) ベトナム産Crescentia cujeteのイリドイドおよびその他の配糖体の成分研究(ポスター発表の部)
- IL-6生産抑制活性を有するサポニン類の研究(II) : 有機化学・天然物化学
- IL-6生産抑制活性を有するサポニン類の研究(I) : 有機化学・天然物化学
- マレーシア産の植物Staurogyne merguensis Kuntzeに含まれる甘味配糖体ストロジンの構造と活性
- ALKALOID FROM BARK OF ALBIZZIA MYRIOPHYLLA
- Saponins from Vietnamese Ginseng, Panax vietnamensis HA et GRUSHV. Collected in Central Vietnam. III
- Saponins from Vietnamese Ginseng, Panax vietnamensis HA et GRUSHV. Collected in Central Vietnam. II
- Screening of Plant Constituents for Effect on Glucose Transport Activity in Ehrlich Ascites Tumour Cells
- Solubilization of Steviolbioside and Steviolmonoside with γ-Cyclodextrin and Its Application to Selective Syntheses of Better Sweet Glycosides from Stevioside and Rubusoside
- Labdane-Type Diterpene Glycosides From Fruits of Rubus foliolosus
- Phenolic Glycosides from Roots of Adenophora tetraphylla Collected in Heilongjiang, China
- Transfructosylation of Rebaudioside A (a Sweet Glycoside of Stevial Leaves) with Microbacterium β-Fructofuranosidase
- Chemical Study on Haematoxylon campechianum : a Sweet Principle and New Dibenz[b, d]oxocin Derivatives
- Studies on Balanites aegyptiaca Fruits, an Antidiabetic Egyptian Folk Medicine
- Phenolic Glycosides from Nuo-Mi-Xang-Cao, a Chinese Acanthaceous Herb
- Minor Cucurbitane-Glycosides from Fruits of Siraitia grosvenori (Cucurbitaceae)
- Saponins from Leaves of Kalopanax pictus (THUNB.) NAKAI, Harigiri : Structures of Kalophanax-Saponins JLa and JLb
- Saponins from Bran of Quinoa, Chenopodium quinoa WILLD. II
- Saponins from Leaves of Kalopanax septemlobus (THUNB.) KOIDZ. : Structures of Kalopanax-saponins La, Lb and Lc
- Reticuloendothelial System-Activating Polysaccharides from Rhizomes of Panax japonicus. : I. Tochibanan-A and -B
- Chemical Studies on the Oriental Plant Drugs. XXXII. Sapogenins from the Roots of Platycodon grandiflorum A. DE CANDOLLE. (3). The Structure of a Prosapogenin, 3-O-β-Glucosylplatycodigenin
- Chemical Studies on the Oriental Plant Drugs. XXXI. Sapogenins of the Roots of Platycodon grandiflorum A. DE CANDOLLE. (2). Structure of Platycodigenin
- Chemical Studies on the Oriental Plant Drugs. XXX. Sapogenins of the Roots of Platycodon grandiflorum A. DE CANDOLLE. (1). Isolation of the Sapogenins and the Stereochemistry of Polygalacic Acid
- Chemical Studies on the Oriental Plant Drugs. XXIX. Saponins and Sapogenins of Ginseng : Further Study on the Chemical Properties of the Side Chain of Dammarane Type Triterpenes
- Chemical Studies on the Oriental Plant Drugs. XXVIII. Saponins and Sapogenins of Ginseng : Stereochemistry of the Sapogenin of Ginsenosides-Rb_1,-Rb_2 and -Rc
- Chemical Studies on the Oriental Plant Drugs. XXVII. The Acid Catalyzed Reactions and the Absolute Configuration at C_ of Dammarane Type Triterpenes
- Chemical Studies on the Oriental Plant Drugs. XXVI. Saponins and Sapogenins of Ginseng. The Absolute Configurations of Cinenic Acid and Panaxadiol
- 47 地衣のトリテルペンの研究 : LobariaおよびPeltigera属について
- Sapogenins of the Roots of Platycodon grandiflorum A. DE CANDOLLE and the Stereochemistry of Polygalacic Acid
- 27 薬用人参のサポニンの化学的研究 : 真性サポゲニンの問題とginsenoside-Rg_1の構造
- Chemical Studies on the Oriental Plant Drugs. XVII. The Prosapogenin of the Ginseng Saponins : Ginsenosides-Rb_1,-Rb_2,and -Rc
- Chemical Studies on the Oriental Plant Drugs. XVI. The Stereochemistry of Protopanaxadiol, a Genuine Sapogenin of Ginseng
- 35 Dammarane系Triterpene,Protopanaxadiol,Betulafolienetriolの側鎖の立体化学
- Chemical Studies on Oriental Plant Drugs. XIV. Protopanaxadiol, a Genuine Sapogenin of Ginseng Saponins
- 9.Penicillium duclauxi Delacroixの代謝産物について
- Studies on the Constituents of Japanese and Chinese Crude Drugs. XII. Panaxadiol, A Sapogenin of Ginseng Roots. (2).
- Studies on the Constituents of Japanese and Chinese Crude Drugs. XI. Panaxadiol, A Sapogenin of Ginseng Roots. (1).
- 25.薬用人參の成分研究 : Panaxadiolの構造
- 4.Penicillium islandicum Soppの色素に関する二、三の知見
- Skyrinの赤外線吸収スペクトルについて
- II-B-8 癌毒素(トキソホルモン - L)を阻害する薬用人参中の酸性多糖体の構造と機能
- Alanysis of Saponins of Wild Panax gineseng
- Study on Saponins of Rhizomes of Panax pseudo-ginseng subsp. himalaicus Collected at Tzatogang and Pari-la, Bhutan-Himalaya
- 菌類代謝産物の研究(第6報)Skyrinの構造について その2
- Endothianin及びRadicalisinのSkyrin及びRugulosinとの同定並びにSkyrinの構造について
- 菌類代謝産物の研究(第4報)Endothia Spp.の色素の分離並びにEndothianin及びRadicalisinのSkyrin及びRugulosinとの同定
- Solubilization of Saponins of Bupleuri Radix with Ginseng Saponins : Effect of Malonyl-ginsenosides on Water Solubility of Saikosaponin-b
- ムクロジ科ムクロジの果皮(延命皮)から単離したmonodesmosideによるラット直腸におけるβ-ラクタム抗生物質の吸収促進作用(発表論文抄録(1986年))
- ムクロジ科ムクロジの果皮(延命皮)から単離したmonodesmosideによるラット小腸におけるβ-ラクタム抗生物質の吸収促進作用(発表論文抄録(1986年))
- Inhibitors of Cyclic AMP Phosphodiesterase in Panax ginseng C. A. MEYER and Panax japonicus C. A. MEYER
- 3,4-Secolupane-Type Triterpene Glycosyl Esters from Leaves of Acanthopanax divaricatus SEEM(Pharmacognosy,Chemical)
- Glycosides from Chinese Medicinal Plant, Hemsleya panacis-scandens, and Structure-Taste Relationship of Cucurbitane Glycosides
- Saponins from Leaves of Kalopanax pictum var. maximowiczii, a Korean Medicinal Plant
- 3,4-Seco-lupane Type Triterpene Glycosyl Esters from a Korean Medicinal Plant, Acanthopanax chiisanensis (Araliaceae)
- 7 エステル型配糖体の研究 : acanthopanax chiisanensisのA-セコトリテルペン配糖体の構造および2-0-グリコシルアラビノシルエステルの^C-NMRについて
- Chemical Constituents of Pericarps of Rosa davurica PALL., a Traditional Chinese Medicine
- Inhibitory Effects of Cucurbitane Triterpenoids on Epstein-Barr Virus Activation and Two-Stage Carcinogenesis of Skin Tumors
- An Additional Sweet Dihydroflavonol Glycoside from Leaves of Engelhardtia chrysolepis, a Chinese Folk Medicine, Huang-qi
- Sweet and Bitter Diterpene-Glucosides from Leaves of Rubus suavissimus
- 7 甘味ステビオール配糖体の研究 : 甘味と構造との相関及び良質甘味剤の酵素合成(口頭発表の部)
- Solubilizing Properties of Glycyrrhizin and Its Derivatives : Solubilization of Saikosaponin-a, the Saponin of Bupleuri Radix
- Application of Borate Ion-Exchange Mode High-Performance Liquid Chromatography to Separation of Glycosides : Saponins of Ginseng, Sapindus mukurossi GAERTN. and Anemone rivularis BUCH.-HAM.
- Nuclear Magnetic Resonance Study on Glycosyl Esters : Glycosyl Esters of 3-O-Acetyloleanolic Acid and Octanoic Acid
- Saponins from Chinese Folk Medicine, "Liang Wang Cha," Leaves and Stems of Nothopanax delavayi, Araliaceae(Pharmacognosy,Chemical)
- Synthesis of the Skeleton of Dammarane-Type Triterpene
- Triterpenes of Japanese White Birch and the Configuration at C-24 of Ocotillol II and Its Related Compounds
- 159) 癌毒素(トキソホルモン-L)を阻害する薬用人参中の多糖体の単離、精製
- Saponins from Panax pseudo-ginseng WALL. subsp. pseudo-ginseng HARA Collected at Nielamu, Tibet, China
- Saponins of Pericarps of Chinese Sapindus delavayi (Pyi-shiau-tzu), a Source of Natural Surfactants
- Chemical Evaluation of Bupleurum Species Collected in Yunnan, China
- 菌類代謝産物の研究(第5報)Skyrinの構造について その1
- Saponins of Plants of Panax Species Collected in Central Nepal and Their Chemotaxonomical Significance. I
- Saponins from Flower-Buds of Panax ginseng Cultivated at Jilin, China
- Saponins from Roots of Kalopanax septemlobus (THUNB.) KOIDZ., Ciqiu : Structures of Kalopanax-saponins C, D, E and F
- Saponins from Leaves of Acanthopanax senticosus HARMS., Ciwujia. II. : Structures of Ciwujianosides A_1,A_2,A_3,A_4 and D_3
- Saponins from Leaves of Acanthopanax senticosus HARMS., Ciwujia : Structures of Ciwujianosides B, C_1,C_2,C_3,C_4,D_1,D_2 and E
- Sweet Dihydroflavonol Rhamnoside from Leaves of Engelhardtia chrysolepis, a Chinese Folk Medicine, Hung-qi
- Saponins of Plants of Panax Species Collected in Central Nepal and Their Chemotaxonomical Significance. II
- Solubilizing Properties of Saponins from Sapindus mukurossi GAERTN.
- 甘味物質--配糖体系甘味物質 (味とにおいの分子認識) -- (味の分子認識)
- 東アジアの植物の化学分類--ベトナム人参及びキイチゴ属植物
- Studies on Mutagenicity of Swertiae Herba. III. : Components Which Become Mutagenic on Nitrite Treatment
- High-Performance Liquid Chromatographic Analysis of Acidic Saponins of Ginseng and Related Plants
- 栽培人参の中性及び酸性サポニンの分析
- Saponins from Brans of Quinoa, Chenopodium quinoa WILLD. I
- 生薬学界,天然薬物研究の今昔(日本生薬学会設立50周年記念)
- 東洋薬物の化学的研究(第25報) : 薬用人参および関連生薬のサポゲニン,サポニンの比較
- ニガキ中のアルカロイドの分析と分布
- タラノキ葉のサポゲニンについて
- シラカンバ葉の成分について
- 天然物化学に関する中国との共同研究
- 10年後の天然物化学に期待するもの(10年後の天然物化学は)
- 天然甘味物質の化学--最近の研究から
- 天然甘味物質の化学--最近の展開