Synthesis of Apogalanthamine Analogues as α-Adrenergic Blocking Agents. XIII. Syntheses of Phenolic 8-Hydroxy-5,6,7,8-tetrahydrodibenz[c, e]azocines
スポンサーリンク
概要
- 論文の詳細を見る
10,11-Diphenolic 8-hydroxy-5,6,7,8-tetrahydrodibenz[c, e]azocine 3,having a partial structure of adrenaline, was prepared by demethylation of the dimethoxyazocine 12 with boron tribromide. The related monophenolic 8-hydroxyazocines 4 and 5 were prepared by cyclization of the dihalogeno-β-phenylethanolamines 6c and 7c with zerovalent nickel, followed by hydrolysis and debenzylation of the O-protected dibenz[c, e]azocines 13 and 14,respectively.
- 社団法人日本薬学会の論文
- 1989-07-25
著者
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小林 茂
Faculty Of Home Economics Shikoku University
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木原 勝
Faculty Of Pharmaceutical Sciences The University Of Tokushima
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今倉 康宏
Faculty of Sciences, Naruto University of Education
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VANGVERAVONG Suwanna
Faculty of Pharmaceutical Sciences, The University of Tokushima
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大西 邦義
Faculty of Pharmaceutical Sciences, The University of Tokushima
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今倉 康宏
Faculty Of Pharmaceutical Sciences The University Of Tokushima
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Vangveravong Suwanna
Faculty Of Pharmaceutical Sciences The University Of Tokushima
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大西 邦義
Faculty Of Pharmaceutical Sciences The University Of Tokushima
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