INTERCONVERSION MODEL ANALYSIS AND ESTIMATION OF AVAILABLE FRACTIONS FOR 4-ACETAMINOBENZALDEHYDE AND ITS REVERSIBLE METABOLITE, 4-ACETAMINOBENZYLALCOHOL, IN THE RAT USING THE MULTI-LINES FITTING TECHNIQUE
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概要
- 論文の詳細を見る
An interconversion model which incorporated a first-pass metabolism was applied to the disposition kinetics of 4-acetaminobenzaldehyde (AB) and its reversible metabolite, 4-acetaminobenzylalcohol (ABA) in the rat. The rates of available fraction of AB, F_<H1>, and of the sequential available fraction of ABA, F_<H2>, were estimated by application of the computer multi-lines fitting technique.
- 公益社団法人日本薬学会の論文
- 1988-05-25
著者
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浅田 昌三
Kobe Women's College of Pharmacy
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中江 裕子
Kobe Women's College Of Pharmacy
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浅田 昌三
Kobe Women's College Of Pharmacy
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大多和 朋子
Kobe Women's College of Pharmacy
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乾 幸子
Kobe Women's College Of Pharmacy
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大多和 朋子
Kobe Women's College Of Pharmacy
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