Changes in the Urinary Constituents in Rats with Chronic Renal Failure during Oral Administration of Rhubarb Extract
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概要
- 論文の詳細を見る
The effect of rhubarb extract on the urinary constituents was examined in rats with chronic renal failure induced by adenine. Orally administered rhubarb extract caused a significant decrease in the urinary excretion of urea. The amount of urinary Na, K, and Ca was significantly reduced in the rhubarb extract-treated rats, while urinary inorganic phosphate was significantly elevated. A polyuria-preventive effect was observed. However, there was no marked change in the amount of urinary creatinine throughout the experimental period. The mechanism of uremia-improving action of rhubarb extract is discussed on the basis of the present results and the previously reported data [Chem. Pharm. Bull., 32,4506 (1984)].
- 社団法人日本薬学会の論文
- 1985-10-25
著者
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奥田 伊津子
Department Of Applied Biochemistry Research Institute For Wakan-yaku Toyama Medical And Pharmaceutic
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横澤 隆子
Department of Applied Biochemistry, Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceut
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大浦 彦吉
Department of Applied Biochemistry, Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceut
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西岡 五夫
Faculty Of Pharmaceutical Sciences Kyushu University
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鈴木 奈緒美
Department of Applied Biochemistry, Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceut
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鈴木 奈緒美
Department Of Applied Biochemistry Research Institute For Wakan-yaku Toyama Medical And Pharmaceutic
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