Effect of Extract from Rhei Rhizoma on Urea-nitrogen Concentration in Rat Serum
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概要
- 論文の詳細を見る
Intraperitoneal administration of the extract from Rhei Rhizoma decreased the urea-nitrogen (BUN) concentration in rat serum. An attempt was made to extract and partially purify the active substance(s), monitoring the BUN-decreasing activity. The activity was detected in the aqueous extract. After partition between butanol and water, biological activity was detected in both fractions. Further purification was carried out by dialysis and Sephadex LH-20 column chromatography, by which small molecular compounds, including anthraquinone glycosides, were eliminated. The BUN-decreasing activity was detected in fractions 3-2-1B, 3-2-2B, and 4-2-3-S1.
- 社団法人日本薬学会の論文
- 1980-06-25
著者
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長沢 哲郎
富山医科薬科大学和漢薬研究所
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大浦 彦吉
Department of Applied Biochemistry, Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceut
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正山 征洋
九大・薬
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渋谷 真也
Department Of Biochemistry Research Institute For Wakan-yaku Toyama Medical And Pharmaceutical Unive
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西岡 五夫
Faculty Of Pharmaceutical Sciences Kyushu University
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渋谷 眞也
富山医科薬科大学和漢薬研究所臨床利用部門
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