Examination of Biodegradability of Poly (ethylene carbonate) and Poly (propylene carbonate) in the Peritoneal Cavity in Rats
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概要
- 論文の詳細を見る
The biodegradability of poly (ethylene carbonate) and poly (propylene carbonate), synthesized from carbon dioxide and alkylene epoxides, was investigated. The biodegradation of poly (ethylene carbonate) pellets in the peritoneal cavity in rats was observable 2 d after implantation and was nearly completed within 2 weeks. The degradation of poly-(propylene carbonate) pellets was not measurable after 2 months. The degradation rate of the pellets made of mixtures of the two types of polycarbonates decreased with increase in poly (propylene carbonate) content. No retardation in body weight gain was observed in polycarbonate-implanted rats. No visible undesirable reaction was observed at the implanted sites.
- 公益社団法人日本薬学会の論文
- 1983-04-25
著者
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従二 和彦
城西大・薬
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吉田 泰彦
東洋大工
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従二 和彦
Faculty Of Pharmaceutical Sciences Josai University
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従二 和彦
Department of Pharmacy, Kumamoto University Hospital
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川口 健夫
Faculty Of Pharmaceutical Sciences Josai University
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井上 祥平
Department Of Synthetic Chemistry Faculty Of Engineering University Of Tokyo
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吉田 泰彦
Department of Applied Chemistry, Faculty of Engineering, Tohyo University
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吉田 泰彦
東洋大
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吉田 泰彦
Department Of Applied Chemistry Faculty Of Engineering Tohyo University
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