Studies on the Syntheses of N-Heterocyclic Compounds. XXIV. Oxidation of Dihydrotetraazanaphthalene Derivatives

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概要

• 論文の詳細を見る

• Oxidation of a variety of substituted dihydrotetraazanaphthalene derivatives (I-IV) with 2,3-dichloro-5,6-dicyanoquinone afforded corresponding dehydrogenated aromatic deriva tives (V, VII, IX, and X). However, oxidation with potassium ferricyanide, bromine or nitrobenzene gave rise to oxidative elimination of the substituent in addition to normal dehydrogenation, depending upon the variety of the substituent. The substi-tuents readily removed by this novel C-C bond cleavage were benzyl, allyl, tert-butyl, cyclohexyl and α-hydroxyalkyl groups.

• 公益社団法人日本薬学会の論文
• 1975-07-25

著者

• 伊藤 克己

  Pharmaceutical Research Laboratories Iii Pharmaceutical Research Division Takeda Chemical Industries

• 万木 庄次郎

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 岡 良和

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 万木 庄次郎

  武田薬品中研

• 伊藤 克已

  Central Research Division Takeda Chemical Industries Ltd.

• 多田 憲生

  Central Research Division, Takeda Chemical Industries, Ltd.

• 多田 憲生

  Central Research Division Takeda Chemical Industries Ltd.

• 多田 憲生

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 伊藤 克己

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 三宅 昭夫

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

• 岡 良和

  Chemistry Laboratories Central Research Division Takeda Chemical Industries Ltd.

• 三宅 昭夫

  Chemistry Laboratories Central Research Division Takeda Chemical Industries Ltd.

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