Studies on the Azasteroids and Related Compounds. V. Syntheses of Isomeric Ethyl 3-Methoxy-2-piperidineacetates and 4-Methoxy-1,2,3,4,4a, 5,7,8,9,10-Decahydro-6H-benzo[c]-quinolizin-6-ones
スポンサーリンク
概要
- 論文の詳細を見る
The lactim ether (XXII), prepared from 3-methoxy-2-piperidone (XXI) by the action of Meerwein reagent, condensed smoothly with benzyl cyanoacetate to give the Cope product (XXIII), which underwent debenzylation and decarboxylation, followed by sodium borohydride reduction and alcoholysis, yielding a mixture of ethyl cis- and trans-3-methoxy-2-piperidineacetates (XXIX). Cyclodehydration of XXIX with cyclohexanone afforded the vinylogous amides (XXX).
- 公益社団法人日本薬学会の論文
- 1969-11-25
著者
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堀井 善一
Faculty Of Pharmaceutical Sciences Josai University
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堀井 善一
Faculty Of Pharmaceutical Sciences Osaka University
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二宮 一弥
Faculty of Pharmaceutical Sciences, Osaka University
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森川 浩一
Faculty of Pharmaceutical Sciences, Osaka University
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二宮 一弥
阪大薬:(現)神戸女子薬科大学
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森川 浩一
Faculty Of Pharmaceutical Sciences Osaka University
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