Antimalarial Activity of Herbal Extracts Used in Traditional Medicine in Korea(Pharmacognosy)
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概要
- 論文の詳細を見る
Aqueous extracts of 6 traditional Korean medicines used to treat malaria were tested in vitro for their antimalarial activity against Plasmodiumfalciparum. The EC_<50> values for the herbal extracts were in the range 1.4-8.1 μg/ml. Significant antimalarial activity was observed with Coptis japonica (EC_<50>= 1.4μg/ml), but it demonstrated no selective toxicity (selectivity=1). In contrast, Kalopanax pictus showed antimalarial activity (EC_<50>=4.6 μg/ml) and higher selective toxicity (>4). This indicated that K. pictus may be potent for a new antimalarial agent.
- 社団法人日本薬学会の論文
- 2003-11-01
著者
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Kim Tae
Department Of Materials Science And Engineering Korea Advanced Institute Of Science And Technology
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KIM Yong
Department of Metallurgy and Materials Science, Hanyang University
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Kim Hye-sook
岡山大学 薬学部
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Kwon Dong-yeul
韓国
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Kwon Dong-yeul
Department Of Oriental Pharmacy College Of Pharmacy Wonkwang University Wonkwang Oriental Medicines
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Park Hyun
Department of Systems Innovation, Graduate School of Engineering, The University of Tokyo
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Kim Tae
Department Of Parasitology College Of Medicine Wonkwang University
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Kim Yong
Department Of Parasitology College Of Medicine Wonkwang University
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KIM Hye-Sook
Faculty of Pharmaceutical Sciences, Okayama University
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WATAYA Yusuke
Faculty of Pharmaceutical Sciences, Okayama University
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Kwon Dong-yeul
Department Of Pathology College Of Oriental Medicine Wonkwang University
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PARK Eun-Kyung
Department of Biochemistry, Kon Kuk University
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KJM Myung
Life Sciences Division, Korea Institute of Science and Technology
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JEON Byung
Department of Pathology, College of Oriental Medicine, Wonkwang University
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AHNN Joohong
Department of Life Science, Kwangju Institute of Science and Technology
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TAKAYA Yoshiaki
Faculty of Pharmacy Meijo University
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Kim M
Kunsan National Univ. Chonbuk Kor
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Kim Hye-sook
Faculty Of Pharmaceutical Sciences Okayama University
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TAKAYA Yoshiaki
Aomori Advanced Industrial Technology Center
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Kjm Myung
Life Sciences Division Korea Institute Of Science And Technology
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Jeon Byung
Department Of Pathology College Of Oriental Medicine Wonkwang University
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Ahnn Joohong
Department Of Life Science Kwangju Institute Of Science And Technology
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Wataya Y
Faculty Of Pharmaceutical Sciences Okayama University
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Wataya Yusuke
Fac. Of Pharmaceutical Sci. Graduate School Of Medicine Dentistry And Pharmaceutical Sci. Okayama Un
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Kim Tae
Department Of Anesthesia And Pain Medicine School Of Medicine Pusan National University
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Park Hyun
Department Of Computer Science Korea Advanced Institute Of Science & Technology
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Kim H‐s
Okayama Univ. Okayama Jpn
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Kim Yong
Department And Research Institute Of Rehabilitation Medicine Yonsei University College Of Medicine
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Kim Eun-jin
Department Of Physiology Institute Of Health Sciences Gyeongsang National University School Of Medic
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Wataya Yusuke
Faculty Of Pharmaceutical Science Graduate School Of Medicine Dentistry And Pharmaceutical Science O
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Kwon Dong-yeul
Department Of Oriental Pharmacy College Of Pharmacy Wonkwang Oriental Medicines Research Institute W
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Park H
Department Of Sport Medicine Kyung-hee University
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Park Hyun
Department Of Computer Science Chungnam National University
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Park Hyun
Department Of Chemical & Biomolecular Engineering Korea Advanced Institute Of Science & Tech
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Park Hyun
Department Of Ceramic Engineering Chonnam National University
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Choo Min-Kyung
Life Sciences Division, Korea Institute of Science and Technology
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Kim Eun-Jin
Department of Applied Physics, Hanyang University, Ansan 426-791, Korea
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Kim Hye-Sook
Faculty of Pharmaceutical Science, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
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KIM Eun-jin
Department of Applied Mathematics, University of Sheffield, Sheffield, S3 7RH, U.K.
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Kim Tae
Department of Advanced Materials Engineering, Sungkyunkwan University, Suwon, Gyeonggi 440-746, Republic Korea
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