Changes in Nitric Oxide Synthas-Containing Neurons in the Brain of Thiamine-Deficient Mice
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概要
- 論文の詳細を見る
We examined nitric oxide synthase (NOS)-containing neurons in thiamine-deficient mice histochemically using NADPH-diaphorase(NADPH-d). Decreases in the number of cell bodies and the densities of fibers in NADPH-d-containing neurons were detected in selective areas of the thalamus, the lateral habenular nucleus, the dorsal raphe nucleus and the medial vestibular nucleus, and decreases in the density of the fibers were also detected in the caudal part of the medial portion of the medial mammillary nucleus in thiamine-deficient mice. A marked loss of NADPH-d-containing neurons was also noted in the hippocampus. The results suggest that NOS is associated with neuropathological vulnerability of the brain in experimental thiamine deficiency.
- 日本組織細胞化学会の論文
著者
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FUSHIKI SHINJI
Department of Clinical Pathology, Kyoto Prefectural University of Medicine
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Takeuchi Yoshihiro
Department of Pediatrics, Shiga University of Medical Science
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Matsushita Hiroko
Department Of Pediatrics Kyoto City Hospital
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Fushiki Shinji
Department Of Clinical Pathology Kyoto Prefectural University Of Medicine:department Of Pathology Ky
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Fushiki Shinji
Department Of Pathology Reserch Institute For Neurological Diseases And Geriatrics
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Kawata Mitsuhiro
Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Japan
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Kawata M
Department Of Anatomy And Neurobiology Kyoto Prefectural University Of Medicine
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Kawata Mituhiro
Department Of Anatomy And Neurobiology Kyoto Prefectural University Of Medicine
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Kawata Mitsuhiro
Department Of Anatomy And Neurobiology Graduate School Of Medical Science Kyoto Prefectural Universi
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SAWADA Tadashi
Departments of Pediatrics, Kyoto Prefectural University of Medicine
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Takeuchi Yoshihiro
Department Of Anatomy Kyoto Prefectural University Of Medicine
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Takeuchi Y
Department Of Pediatrics Shiga University Of Medical Science
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Sawada T
Department Of Pathology Tokyo Women's Medical University
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Sawada Tadashi
Department Of Electrical Engineering Kyoto University:(present Office)jr Central
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KOSAKA Kitaro
Department of Pediatrics, Kyoto Prefecture University of Medicine
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Kosaka Kitaro
Department Of Pediatrics
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Matsushita Hiroko
Department Of Pediatrics Kyoto Prefectural University Of Medicine
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Sawada Tatsuo
Department Of Pathology Tokyo Women's Medical College
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Matsushita Hiroko
京都府立医科大学 小児科
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TAKEUCHI Yoshihiro
Department of Pediatrice, Kyoto Prefectural University of Medicine:Department of Pediatrics, Shiga University of Medical Science
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