前立腺梗塞の病理組織学的研究

概要

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Infarction of the prostate in hyperplastic glands is more frequent than generally supposed. In120 cases of hyperplastic prostates, twenty-four instances of infarction were found, constituting in frequency of 20 per cent. The lesion of iufarction, which occurs only in hyperplastic nodule, consists of foci of coagulation necrosis involving epithelial and stromal elements. Squamous epithelial metaplasia, as well as the so-called "regenerating epithelial dysplasia", frequently develops around the periphery of an area of infarction. These epithelial changes may mislead one into considering the conditions as a malignant tumor, when he is unaquainted with this process. The significance of epithelial metaplasia or dysplasia in the differential diagnosis from carcinoma should be noticed. In cases with infarction, the average weight of enucleated glands increased by more than 50%, the attacks of urinary retention occurred 1.7 times more frequent and the duration of symptoms was 20 months shorter, as compared to those in cases without infarction.
社団法人日本泌尿器科学会の論文