経頭蓋的磁気刺激における渦電流の有限要素解析および精神疾患治療のための至適刺激条件の検討(生体磁気・医療応用)

概要

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Current distributions in transcranial magnetic stimulation (TMS) were calculated under various conditions and compared with the current distribution in electroconvulsive therapy (ECT) in order to find an optimum condition of TMS as an alternative to ECT. Current distributions in TMS were obtained for the following coil shapes and coil diameters : circular coils of 50mm, 75mm, 100mm, 125mm, and 150mm, and figure-eight coils of 50mm, 75mm, 100mm, and 125mm. Stimulus parameters in TMS were evaluated using a performance function F which increases with the difference in the current distributions between ECT and TMS. The minimum value of F decreased with an increase in the coil diameter. In the case of a 150-mm circular coil, the performance function had a minimum value of 6.3 A^2/m^4 at a coil current of 29 kA, which corresponded to a magnetic flux density of 0.24 T. A coil position on the forehead and the use of a large circular coil gave better results.
社団法人日本磁気学会の論文
2005-05-01