強磁場下での赤血球の酸素結合解離過程について

概要

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We investigated the possible effects of magnetic fields on the oxidation and deoxidation of hemoglobin in red blood cells. We observed a change in the oxidation rate of a red blood cell solution by measuring the change in the absorbance of red blood cells at 560 nm in both, an equilibrium state and a nonequilibrium state. The change in the absorbance of hemoglobin in an equilibrium state under a 14-T magnetic field was not significant. However, we obtained a minute change in the absorbance of hemoglobin in an equilibrium state during field exposure. When the red blood cell solution was not in contact with air, the the absorbance did not change. The influence of contact with open air was significant, especially in a nonequilibrium state. We concluded that the oxidation of hemoglobin in a blood cell solution was enhanced by the change in the composition of the atmosphere surrounding the optical cell, and by convection caused by gradient magnetic fields. The possibility of a 14-T magnetic field affecting the oxidation of a blood cell itself was also suggested.
社団法人日本磁気学会の論文
1998-04-15