Synthesis of (R)-1,3-Butanediol by Enantioselective Oxidation Using Whole Recombinant Escherichia coli Cells Expressing (S)-Specific Secondary Alcohol Dehydrogenase(Microbiology & Fermentation Technology)

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概要

• 論文の詳細を見る

• The synthesis of (R)-1,3-butanediol (BDO) from its racemate was studied using whole cells of recombinant Escherichia coli expressing an (S)-specific secondary alcohol dehydrogenase (CpSADH) from Candida parapsilosis by enantioselective oxidation. Under the optimized conditions, the yield of (R)-1,3-BDO reached 72.6 g/l, with a molar recovery yield of 48.4% from a racemate of 15% and an optical purity of 95% ee.

• 社団法人日本農芸化学会の論文
• 2002-04-23

著者

• KOBAYASHI Yoshinori

  Tsukuba Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• Kobayashi Y

  Daicel Chemical Industries Ltd. Ibaraki Jpn

• Yamamoto H

  Life Science Development Center Cpi Company Daicel Chemical Industries Ltd. Tsukuba Research Center

• Yamamoto Hiroaki

  Life Science Development Center Cpi Company Daicel Chemical Industries Ltd. Tsukuba Research Center

• Kobayashi Yoshinori

  Life Science Development Center Cpi Company Daicel Chemical Industries Ltd. Tsukuba Research Center

• MATSUYAMA Akinobu

  Corporate Development Center, Daicel Chemical Industries, Ltd., Tsukuba Research Center

• YAMAMOTO Hiroaki

  Tsukuba Research Center, Daicel Chemical Industries, Ltd.

• MATSUYAMA Akinobu

  Tsukuba Research Center, Daicel Chemical Industries, Ltd.

• Yamashita H

  Mathematical Systems Inc.

• Matsuyama A

  Corporate Development Center Daicel Chemical Industries Ltd. Tsukuba Research Center

• Kobayashi Yoshinori

  Tsukuba Laboratory P.c.c. Technology Inc. C/o Tsukuba Research Laboratories Kyowa Hakko Kogyo Co. Lt

• Yamamoto Hiroaki

  Tsukuba Research Center Daicel Chemical Industries Ltd.

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