Effects of Chemical Modification of Carboxyl Groups in the Hemolytic Lectin CEL-III on Its Hemolytic and Carbohydrate-Binding Activities

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概要

• 論文の詳細を見る

• Effects of chemical modification of carboxyl groups in the hemolytic lectin CEL-III on its activities were investigated. When carboxyl groups were modified with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) and glycine methyl ester, hemolytic activity of CEL-III decreased as the EDC concentration increased, accompanied by reduction of oligomerization ability and hemagglutinaing activity. However, binding ability of CEL-III for immobilized lactose was retained fairly well after modification, suggesting that one of two carbohydrate-binding sites might be responsible for such inactivation of CEL-III.

• 社団法人日本農芸化学会の論文
• 2000-06-23

著者

• HATAKEYAMA Tomomitsu

  Department of Applied Chemistry, Faculty of Engineering, Nagasaki University

• Hatakeyama T

  Department Of Applied Chemistry Faculty Of Engineering Nagasaki University

• Hatakeyama Tomomitsu

  Laboratory Of Biochemistry Faculty Of Agriculture Kyushu University:(present Address)dept. Of Applie

• Aoyagi H

  Department Of Applied Chemistry Faculty Of Engineering Nagasaki University

• Aoyagi H

  Kyushu Nutrition Welfare University

• AOYAGI Haruhiko

  Department of Applied Chemistry, Faculty of Engineering, Nagasaki University

• Tomomitsu Hatakeyama

  Department Of Applied Chemistry Faculty Of Engineering Nagasaki University

• Kodama H

  Department Of Chemistry Faculty Of Science And Engineering Saga University

• Kuwahara H

  Department Of Chemistry Faculty Of Science And Engineering Saga University

• Kodama Hiroaki

  東京理科大学 薬学部分子病態学

• KUWAHARA Hiromiki

  Department of Applied Chemistry, Faculty of Engineering, Nagasaki University

• FUNADA Takako

  Department of Applied Chemistry, Faculty of Engineering, Nagasaki University

• Hatakeyama Tomomitsu

  Department Of Agricultural Chemistry Faculty Of Agriculture Kyushu University

• Aoyagi Haruhiko

  Department Of Applied Chemistry Faculty Of Engineering Nagasaki University

• Aoyagi Haruhiko

  Faculty Of Pharmaceutical Science:faculty Of Science:kyushu University

• Funada Takako

  Department Of Applied Chemistry Faculty Of Engineering Nagasaki University

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