Effects of Chemical Modification of Carboxyl Groups in the Hemolytic Lectin CEL-III on Its Hemolytic and Carbohydrate-Binding Activities
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概要
- 論文の詳細を見る
Effects of chemical modification of carboxyl groups in the hemolytic lectin CEL-III on its activities were investigated. When carboxyl groups were modified with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) and glycine methyl ester, hemolytic activity of CEL-III decreased as the EDC concentration increased, accompanied by reduction of oligomerization ability and hemagglutinaing activity. However, binding ability of CEL-III for immobilized lactose was retained fairly well after modification, suggesting that one of two carbohydrate-binding sites might be responsible for such inactivation of CEL-III.
- 社団法人日本農芸化学会の論文
- 2000-06-23
著者
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HATAKEYAMA Tomomitsu
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University
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Hatakeyama T
Department Of Applied Chemistry Faculty Of Engineering Nagasaki University
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Hatakeyama Tomomitsu
Laboratory Of Biochemistry Faculty Of Agriculture Kyushu University:(present Address)dept. Of Applie
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Aoyagi H
Department Of Applied Chemistry Faculty Of Engineering Nagasaki University
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Aoyagi H
Kyushu Nutrition Welfare University
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AOYAGI Haruhiko
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University
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Tomomitsu Hatakeyama
Department Of Applied Chemistry Faculty Of Engineering Nagasaki University
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Kodama H
Department Of Chemistry Faculty Of Science And Engineering Saga University
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Kuwahara H
Department Of Chemistry Faculty Of Science And Engineering Saga University
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Kodama Hiroaki
東京理科大学 薬学部分子病態学
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KUWAHARA Hiromiki
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University
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FUNADA Takako
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University
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Hatakeyama Tomomitsu
Department Of Agricultural Chemistry Faculty Of Agriculture Kyushu University
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Aoyagi Haruhiko
Department Of Applied Chemistry Faculty Of Engineering Nagasaki University
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Aoyagi Haruhiko
Faculty Of Pharmaceutical Science:faculty Of Science:kyushu University
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Funada Takako
Department Of Applied Chemistry Faculty Of Engineering Nagasaki University
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