Growth Suppressing Activity for Endothelial Cells Induced from Macrophages by Carboxymethylated Curdlan
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概要
- 論文の詳細を見る
A carboxymethylated derivative of a linear (1→3)-β-D-glucan (CMCD) from Alcaligenes faecalis var. myxogenes acted directly on mouse peritoneal macrophages and mouse lymphoma P388D1 cells, and induced a growth suppressing activity for bovine artery endothelial cells (BAEs) from themselves at a concentration of 100μg/ml. The suppressing activity was also detected in the mouse serum administered as an i.p. injection of CMCD at a dose of 100mg/kg, suggesting that the growth suppressing activity was induced from macrophages potentiated by CMCD in vivo.
- 社団法人日本農芸化学会の論文
- 1997-11-23
著者
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USUI Shigeyuki
Department of Pharmaceutics, Gifu Pharmaceutical University
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KIHO Tadashi
Department of Pharmaceutics, Gifu Pharmaceutical University
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UKAI Shigeo
Department of Pharmaceutics, Gifu Pharmaceutical University
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Kiho T
Gifu Prefectural Institute Of Health And Environmental Sciences
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Kiho Tadashi
Gifu Pharmaceutical University
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Usui Shigeyuki
Laboratory Of Pharmaceutics Gifu Pharmaceutical University
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Ukai S
Gifu Pharmaceutical Univ. Gifu Jpn
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Kiho T
Gifu Pharmaceutical Univ. Gifu Jpn
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Matsunaga Toshiyuki
Department Of Biochemistry Research Center For Genomic Medicine Saitama Medical School
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