Production of d-β-Hydroxyisobutyric Acid from Isobutyric Acid by Candida rugosa and Its Mutant : Studies on β-Hydroxycarboxylic Acids (III)

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概要

• 論文の詳細を見る

• The optimum conditions for production of D-β-hydroxyisobutyric acid by Candida rugosa IFO 0750 and its mutant lacking β-hydroxyisobutryrate dehydrogenase were studies. Under the favorable conditions, the parent strain produced 21.7 mg/ml of D-β-hydroxyisobutyric acid on 72 h-cultivation, but the molar yield of the β-hydroxy acid was less than 50%. The mutant lacking β-hydroxyisobutyrate dehydrogenase needed an energy source for conversion of isobutyridc acid to D-β-hydroxyisobutyric acid. The yield of D-β-hydroxyisobutyric acid from isobutyric acid by the mutant increased to approximately 96%.

• 社団法人日本生物工学会の論文
• 1982-12-25

著者

• Hasegawa J

  Biochemical Research Laboratories Kanegafuchi Chemical Industry Co. Ltd.

• KAWAHARADA Hajime

  Biochemical Research Laboratories, Kanegafuchi Chemical Industry Co., Ltd.

• WATANABE Kiyoshi

  Biochemical Research Laboratories, Kanegafuchi Chemical Industry Co., Ltd.

• Hasegawa J

  Kaneka Corp. Hyogo Jpn

• HASEGAWA Junzo

  Biochemical Research Laboratories, Kanegafuchi Chemical Industry Co., Ltd.

• OGURA Masahiro

  Biochemical Research Laboratories, Kanegafuchi Chemical Industry Co., Ltd.

• Hasegawa Junzo

  Biochemical Research Laboratories Kanegafuchi Chemical Industry Co. Ltd.

• Watanabe Kiyoshi

  Biochemical Research Laboratories Kanegafuchi Chemical Industry Co. Ltd.

• Ogura Masahiro

  Biochemical Research Laboratories Kanegafuchi Chemical Industry Co. Ltd.

• KANEMA HIROSHI

  Biochemical Research Laboratories, Kanegafuchi Chemical Industry, Co., Ltd.,

• NODA NORIO

  Biochemical Research Laboratories, Kanegafuchi Chemical Industry, Co., Ltd.,

• Noda Norio

  Biochemical Research Laboratories Kanegafuchi Chemical Industry Co. Ltd.

• Kanema Hiroshi

  Biochemical Research Laboratories Kanegafuchi Chemical Industry Co. Ltd.

• Kawaharada Hajime

  Biochemical Research Laboratories Kanegafuchi Chemical Industry Co. Ltd.

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