Effect of Post-prandial Posture on Orocecal Transit Time and Digestion of Milk Lactose in Humans

概要

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We examined the effect of post-prandial body posture on orocecal transit time and absorption of milk lactose using the breath hydrogen test. In this experiment, subjects ingested a cup of commercially available milk to which we had added a small amount of lactosucrose (an indigestible trisaccharide), and then they lay on their backs or sat on a chair for the first 4 hr (from 08:00 to 12:00). After four hours lying or sitting, they remained sedentary on a sofa for the second six hr (from 12:00 to 18:00). Participants' end alveolar breath samples were collected every 15 min from 08:00 to 12:30, then every 30min from 13:00 to 18:00. The experiment was conducted on two consecutive days using a randomized, crossover Atudy design. Examination showed that the orocecal transit time of the oligosaccharides (lactosucrose and milk lactose) under the post-prandial supine condition was significantly longer than that under the sitting condition. In addition, the amount of breath hydrogen excretion under the supine condition was significantly lower than under the sitting condition, indicating that the unabsorbed milk lactose moved into cecum under the supine condition is smaller than that under the sitting condition. These findings provide evidence that postprandial supine posture works more beneficially to digest and absorb milk lactose when compared to the sitting posture.
日本生理人類学会の論文