Alteration of .BETA.-D-Glucan from Edible Mushroom after Injection into Mouse Peritoneal Cavity.
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概要
- 論文の詳細を見る
Tritium-labeled antitumor β-D-glucan derivative (T-labeled glucan) was prepared from the branched β-1, 3-D-glucan of an edible mushroom, Volvariella volvacea, by its periodate oxidation followed by reduction with NaBT4. Twenty-three hours after T-labeled glucan had been injected into the mouse peritoneal cavity, about 3% of the total radioactivity injected was found in the mouse serum. In spite of the fact that T-labeled glucan had no affinity to the anion-exchange column before injection, about 50% of the labeled β-D-glucan in the serum thus obtained was adsorbed onto the column. The labeled β-D-glucan fraction eluted from the column by salt gradient showed antitumor activity in vivo.
- 財団法人 学会誌刊行センターの論文
著者
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Sone Yoshiaki
Department Of Food And Nutrition Faculty Of Human Life Science
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Misaki Akira
Department Of Food And Nutrition Faculty Of Human Life Science Osaka City University
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Shibata Satoaki
Department Of Food And Nutrition Faculty Of Science Of Living Osaka City University
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Sone Yoshiaki
Department of Food and Nutrition, Faculty of Human Life Science, Osaka City University
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Misaki Akira
Department of Food and Nutrition, Faculty of Human Life Science, Osaka City University
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KISHIDA Etsu
Department of Food and Nutrition, Faculty of Human Life Science, Osaka City University
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SHIBATA Satoaki
Department of Food and Nutrition, Faculty of Human Life Science, Osaka City University
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