Prognosis of Primary Malignant Lymphoma of the Central Nervous System : A Retrospective Study of 32 Cases
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概要
- 論文の詳細を見る
A retrospective analysis of 32 patients with primary malignant lymphoma of the central nervous system (CNS) diagnosed between 1976 and 1989 investigated treatment results and recurrence patterns. All patients showed either complete or partial regression of the tumor after initial treatment, mainly radiation therapy with adjuvant chemotherapy. The mean dose of whole-brain irradiation was 40.9Gy and that of booster was 14.4Gy. Most patients had tumor recurrence. The median time to recurrence from completion of the treatment was 5 months. The 1- and 5-year survival rates were 50.0 and 17.7%, respectively, and the overall median survival time was 11 months. Most tumors had multiple recurrences at the primary site and other regions of the CNS, and tended to recur in the periventricular region and the cerebrospinal fluid space. Spinal metastasis occurred in five cases. The importance of good control of the primary lesion and active maintenance therapy for the whole CNS is emphasized.
- 日本脳神経外科学会の論文
- 1992-10-15
著者
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WATANABE Masato
Department of Energy Sciences, Tokyo Institute of Technology
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Watanabe Masato
Department Of Energy Sciences Tokyo Institute Of Technology
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TAKEDA NORIO
Department of Applied Microbial Technology, Kumamoto Institute of Technology
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TANAKA Ryuichi
Department of Neurosurgery, Brain Research Institute, Niigata University
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HONDO Hiroaki
Department of Neurosurgery, Toyama Prefectural Central Hospital
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ONDA Kiyoshi
Department of Neurosurgery, Brain Research Institute, Niigata University
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Hondo Hiroaki
Department Of Neurosurgery Brain Research Institute Niigata University
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Hondo Hiroaki
Department Of Neurosergery Toyama Prefectural Central Hospital
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Onda Kiyoshi
Departments Of Neurosurgery Brain Research Institute Niigata University
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Takeda Norio
Department Of Applied Microbial Technology Kumamoto Institute Of Technology
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Tanaka Ryuichi
Departments Of Neurosurgery Brain Research Institute Niigata University
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Tanaka R
Department Of Neurosurgery Brain Research Institute Niigata University
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Tanaka Ryuichi
Department Of Neurosurgery Brain Research Institute Niigata University
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Onda Kiyoshi
Department Of Neurosurgery Brain Research Institute Niigata University
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FUSEJIMA Toru
Department of Neurosurgery, Brain Research Institute, Niigata University
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Fusejima Toru
Department Of Neurosurgery Brain Research Institute Niigata University
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Watanabe Masato
Department Of Neurosurgery Brain Research Institute Niigata University
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Tanaka Ryuichi
Department Of Liberal Arts Faculty Of Science And Technology Tokyo University Of Science
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