Effect of Acquired Tolerance to Ischemia on Focal Infarction in Gerbils
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概要
- 論文の詳細を見る
The protective effect of prior ischemia on focal cerebral infarction produced by permanent middle cerebral artery (MCA) occlusion was studied in a gerbil model. Forebrain ischemia for 2 and 5 minutes at an interval of 48 hours was used as the prior ischemic insult. Forty-eight hours after the second forebrain ischemia, the MCA was occluded. Progression of ischemic change caused by the MCA occlusion was delayed in the early ischemic period in animals with prior ischemia, as compared to animals without prior ischemia. The mean infarct volume 24 hours after the MCA occlusion was the same in animals with and without prior ischemia. Ischemic tolerance was acquired in this model, but had no effect on the extent of infarction caused by permanent ischemia.
- 日本脳神経外科学会の論文
- 1997-03-15
著者
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Abe Hiroshi
Department Of Cardiology National Cardiovascular Center
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TANAKA Ryuichi
Department of Neurosurgery, Brain Research Institute, Niigata University
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SORIMACHI Takatoshi
Department of Neurosurgery, Nishiogi-chuo Hospital
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TAKEUCHI Shigekazu
Department of Neurosurgery,Brain Research Institute,Niigata University
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Takeuchi Shigekazu
Department Of Neurosurgery Brain Research Institute Niigata University
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Tanaka Ryuichi
Department Of Neurosurgery Brain Research Institute Niigata University
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Abe Hiroshi
Department Of Anatomy Akita University School Of Medicine
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Sorimachi Takatoshi
Department Of Neurological Surgery Niigata Rosai Hospital:m.d. Department Of Neurosurgery Brain Rese
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Abe Hiroshi
Department Of Anatomy Akita University Graduate School Of Medicine And Faculty Of Medicine
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Abe Hiroshi
Department Of Neurosurgery Brain Research Institute Niigata University
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Abe Hiroshi
Department Of Agricultural Chemistry Faculty Of Agriculture Tohoku University
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Tanaka Ryuichi
Department Of Liberal Arts Faculty Of Science And Technology Tokyo University Of Science
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反町 隆俊
Department of Neurosurgery, Brain Research Institute, Niigata University
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