Dystrophic Axonal Formation (Spheroid Body) in Central Neurocytoma : Case Report

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概要

• 論文の詳細を見る

• A 30-year-old female presented with a central neurocytoma manifesting as positional headache. Magnetic resonance imaging showed a large calcified mass in the right lateral ventricle. The tumor was completely removed surgically. Light microscopy showed a linear arrangement of well-defined cells (beaded-string pattern) containing small round nuclei with abundant perikarya. A perinuclear halo reminiscent of oligodendroglioma was prominent in some cell groups. The tumor was entirely amitotic and free of atypia. Large, plump spheroid bodies lacking nuclei but containing coarse brown pigments were present among the tumor cells. The tumor cells were immunoreactive to neuron-specific enolase and synaptophysin but not glial fibrillary acidic protein or neurofilament. The ultrastructure of the tumor cells included abundant spheroid bodies containing secretory granules around neurons, indicating a dystrophic or aborted process of neuronal differentiation rather than a completely-differentiated central neurocytoma.

• 日本脳神経外科学会の論文
• 1993-08-15

著者

• Tada Mitsuhiro

  北海道大学 脳神経外科

• Tada Mitsuhiro

  Department Of Neurosurgery University Of Hokkaido School Of Medicine

• Abe Hiroshi

  Department Of Cardiology National Cardiovascular Center

• Abe Hiroshi

  Department Of Neurosurgery Hokkaido University Graduate School Of Medicine

• SAWAMURA Yutaka

  Department of Neurosurgery, Hokkaido University Hospital

• AIDA Toshimitsu

  Department of Neurosurgery, Hokkaido University School of Medicine

• Nagashima K

  Laboratory Of Molecular And Cellular Pathology Hokkaido University Graduate School Of Medicine

• Nagashima Kazuo

  北海道大学 獣医学部応用獣医学

• DIRAZ Ahmed

  Department of Neurosurgery Hokkaido University School of Medicine

• MURATA Jun-ichi

  Department of Neurosurgery Hokkaido University School of Medicine

• NAGASHIMA Kazuo

  The Second Department of Pathology, Hokkaido University School of Medicine

• Abe Hiroshi

  Department Of Neurosurgery University Of Hokkaido School Of Medicine

• Nagashima Kazuo

  Laboratory Of Molecular And Cellular Pathology Hokkaido University Graduate School Of Medicine

• Tada Mitsuhiro

  Department Of Chemistry Faculty Of Science Kochi University

• Sawamura Yutaka

  Department Of Neurosurgery University Of Hokkaido School Of Medicine

• Sawamura Yutaka

  Department Of Bioresource Science Faculty Of Agriculture Kagawa University

• Abe Hiroshi

  Department Of Anatomy Akita University School Of Medicine

• Nagashima Kazuo

  Departments Of Pathology Hokkaido University School Of Medicine

• Suwamura Yutaka

  Department Of Neurosurgery Hokkaido University School Of Medicine

• Aida Toshimitsu

  Department Of Neurosurgery Hokkaido University School Of Medicine

• Nagashima Kazuo

  Pathology Sapporo Higashi-tokushukai Hospital

• Aida Toshimitsu

  Department Of Neurosurgery Hokkaido University School Of Medicine:m.d. Department Of Neurosurgery Ha

• Abe Hiroshi

  Department Of Agricultural Chemistry Faculty Of Agriculture Tohoku University

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