Effect of Hypoxia on Proliferation of Microvascular Endothelial Cells Derived from Mongolian Gerbil Brain
スポンサーリンク
概要
- 論文の詳細を見る
This study investigated the effect of hypoxia on the proliferation of microvascular endothelial cells in the brain. Endothelial cells derived from microvessels of Mongolian gerbil brain and control cells (3T3) were incubated for 7 days under various hypoxic and normoxic conditions at 37℃. The proliferation of endothelial cells was inhibited by severe hypoxia, but stimulated by moderate hypoxia. No significant effect of hypoxia on the proliferation of control cells was observed. Endothelial cell-conditioned medium cultured under moderate hypoxia did not affect the growth of endothelial cells. The stimulatory effect of moderate hypoxia on the proliferation of cultured endothelial cells is due to an inherent property of brain endothelial cells.
- 日本脳神経外科学会の論文
- 1994-12-15
著者
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WATANABE Masato
Department of Energy Sciences, Tokyo Institute of Technology
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Watanabe Masato
Department Of Energy Sciences Tokyo Institute Of Technology
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MINAKAWA Takashi
Department of Neurosurgery, Akita Red Cross Hospital
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Minakawa Takashi
Department Of Neurosurgery Brain Research Institute Niigata University
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Minakawa Takashi
Department Of Neurosurgery Akita Red Cross Hospital
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FUJII Yukihiko
Department of Neurosurgery, Brain Research Institute, University of Niigata
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TANAKA Ryuichi
Department of Neurosurgery, Brain Research Institute, Niigata University
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TAKEUCHI Shigekazu
Department of Neurosurgery,Brain Research Institute,Niigata University
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Takeuchi Shigekazu
Department Of Neurosurgery Brain Research Institute Niigata University
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Tanaka Ryuichi
Department Of Neurosurgery Brain Research Institute Niigata University
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Fujii Yukihiko
Department Of Neurosurgery Brain Research Institute Niigata University
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KOIKE Tetsuo
Department of Neurosurgery, Brain Research Institute, Niigata University
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Koike Tetsuo
Department Of Neurosurgery Brain Research Institute Niigata University
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Tanaka Ryuichi
Department Of Liberal Arts Faculty Of Science And Technology Tokyo University Of Science
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