Giant Cell Reparative Granuloma of the Temporal Bone : Neuroradiological and Immunohistochemical Findings
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概要
- 論文の詳細を見る
A 38-year-old man presented with a giant cell reparative granuloma (GCRG) of the left temporal bone. Computed tomography showed a osteolytic middle cranial masslesion. Magnetic resonance (MR) imaging showed the lesion as low intensity with heterogeneous enhancement by gadolinium on the T_1-weighted images, and extremely low intensity on the T_2-weighted images. Angiography showed the lesion as highly vascular and fed by branches of the left external carotid artery. After preoperative embolization, gross total removal of the tumor was performed. The postoperative course was uneventful and no evidence of recurrence has been found for more than 4 years. Histological examination revealed GCRG with multinucleated giant cells in the fibrous background, abundant collagen bundles, hemosiderin deposits, and trabeculae of reactive bone. Some of the mononuclear stromal cells and almost all of the giant cells were positive for CD68, suggesting histiocytic differentiation. These histological features reflect the marked decrease in signal intensity on T_2-weighted MR images.
- 日本脳神経外科学会の論文
- 2002-11-15
著者
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Onda Kiyoshi
Departments Of Neurosurgery Brain Research Institute Niigata University
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Tanaka Ryuichi
Departments Of Neurosurgery Brain Research Institute Niigata University
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Tanaka R
Department Of Neurosurgery Brain Research Institute Niigata University
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Tanaka Ryuichi
Department Of Neurosurgery Brain Research Institute Niigata University
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TAKAHASHI Hitoshi
Pathology and Brain Disease Research Center, Brain Research Institute, Niigata University
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Onda Kiyoshi
Department Of Neurosurgery Brain Research Institute Niigata University
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Yoshimura Junichi
Departments Of Neurosurgery Brain Research Institute Niigata University:(present Address)department
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Yoshimura Junichi
Department Of Anesthesiology And Critical Care Medicine Faculty Of Medicine Kyushu University
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Takahashi H
Departments Of Pathology Brain Research Institute Niigata University
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Tanaka Ryuichi
Department Of Liberal Arts Faculty Of Science And Technology Tokyo University Of Science
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