Preliminary Results of Interstitial ^<192>Ir Brachytherapy for Malignant Gliomas
スポンサーリンク
概要
- 論文の詳細を見る
Twenty-six patients with recurrent or unremovable malignant gliomas were treated by interstitial brachytherapy with iridium-192 seeds. Stereotactic implantation of the afterloading catheters using the Brown-Roberts-Wells computed tomography (CT)-guided stereotactic system was performed in 24 patients and surgical implantation in two patients with pontine glioma. The response to therapy was measured by serial CT, magnetic resonance imaging, and clinical examination. Tumor regression was seen in 17 patients 1-3 months after implantation. Tumor progression was seen in only three patients. After interstitial brachytherapy, the most commonly observed CT finding was central low density. Median survival time was 18 months after implantation. Autopsies in five patients revealed the delayed effects of radiation injury such as typical vascular changes, microcalcification, and coagulative necrosis in the implant area and tumor recurrence at the periphery. The results suggest that brachytherapy is not curative but prolonged the median survival time by 6 months.
- 日本脳神経外科学会の論文
- 1992-09-15
著者
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松本 健五
信州大学 脳神経外科
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Hiraki Yoshio
Departments Of Neurologicol Badiology Okayama University Medical School
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Hiraki Yoshio
Department Of Radiology Okayama University Medical School
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Nakagawa Tomio
Department Of Hematology Oncology And Respiratory Medicine Graduate School Of Medicine And Dentistry
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Ohmoto Takashi
Department Of Neurological Surgery Okayama University Medical School
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Matsumoto Kengo
Department Of Cardiology National Hospital Organization Kure Medical Center
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Higashi Hisato
Department Of Neurological Surgery Okayama University Medical School
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NAKAGAWA MINORU
Department of Neurological Surgery
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MISHIMA Nobuya
Department of Neurological Surgery, Okayama University Medical School
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TAGUCHI Kohji
Department of Clinical Pathology, Okayama University Hospital
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Furuta Tomohisa
Department Of Neurological Surgery Okayama University Medical School
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Furuta Tomohisa
Department Of Biochemistry Fukushima Medical University
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Nakagawa Minoru
Department Of Neurological Surgery Okayama University Medical School
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Taguchi Kohji
Department Of Clinical Pathology Okayama University Hospital
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MAESHIRO Tomohide
Department of Neurological Surgery, Okayama University Medical School
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TSUNO Kazuyuki
Department of Neurological Surgery, Okayama University Medical School
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Tsuno Kazuyuki
Department Of Neurological Surgery Okayama University Medical School
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Mishima Nobuya
Department Of Neurological Surgery Okayama University Medical School
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Maeshiro Tomohide
Department Of Neurological Surgery Okayama University Medical School
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Ohmoto Takashi
Department Of Neurological Surgery Kagawa Medical School
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NAKAGAWA Tomio
Department of Radiology Okayama Universtiy Medical Scool
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FURUTA Tomohisa
Department of Neurological Surgery, Okayama, University Medical School
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OHMOTO Takashi
Department of Neurological Surgery, Okayama University Medical, School
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OHMOTO Takashi
Department of Environmental Technology, Osaka Municipal Technical Research Institute
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