Co-localization of Human Growth Hormone and Human Prolactin in Hormonally Pure Human Growth Hormone-producing Pituitary Adenomas
スポンサーリンク
概要
- 論文の詳細を見る
成長ホルモン(GH)産生下垂体腺腫におけるGHとプロラクチン(PRL)の共存について調べた。対象は5例のGH産生腺腫でいずれも血中PRLは正常範囲内であった。はじめに抗GH、PRLのポリクローナル抗体を反応させて、それぞれ異なる大きさの金コロイドで標識する免疫電顕(二重染色)の手法を用いた。その結果、5例中1例(症例2)で同一顆粒内にGHとPRLの共存を認めた。次に抗GH、PRLのモノクローナル抗体を用いて、Western-blotting法を行ったところ、5例中3例にGH、PRLの種々の濃淡のバンドが見られた。GH産生腺腫にPRLが共存することは良く知られた事実であるが、その割合は個々の症例によって異なっており、このことがGH産生腺腫の病態の多様性を説明する一つの要素であることが示唆された。
- 日本脳神経外科学会の論文
- 1998-06-15
著者
-
黒崎 雅道
鳥取大学脳神経外科
-
Kawakami Hayato
Department of Anatomy, Kyorin University School of Medicine
-
WATANABE Takashi
Division of Neurosurgery, Institute of Neurological Sciences
-
HORI Tomokatsu
Division of Neurosurgery, Institute of Neurological Sciences
-
HIRAI Kazumitsu
Department of Medical Zoology, Tottori University School of Medicine, Yonago
-
HIRANO Hiroshi
Department of Anatomy, Kyorin University School of Medicine
-
Kawakami Hayato
Department Of Anatomy Kyorin University School Of Medicine
-
Kawakami Hayato
Department Of 2nd Anatomy Kyorin University School Of Medicine
-
Hori Tomokatsu
Division Of Neurosurgery Institute Of Neurological Sciences
-
Hirai Kazumitsu
Department Of Medical Zoology Tottori University School Of Medicine Yonago
-
Hirai Kazumitsu
Department Of Medical Zoology Faculty Of Medicine Tottori University
-
Hirano Hiroshi
Department Of Anatomy Kyorin University School Of Medicine
-
Hirano Hiroshi
Department Of Anatomy Kansai Medical School
-
Hirano Hiroshi
Department Of 2nd Anatomy Kyorin University School Of Medicine
-
Watanabe Takashi
Division Of Neurosurgery Department Of Brain And Neurosciences Faculty Of Medicine Tottori Universit
-
黒崎 雅道
鳥取大学脳神経医科学講座脳神経外科学分野
-
Watanabe Takashi
Division Of Gastroenterology Tohoku University Graduate School Of Medicine
-
Watanabe Takashi
Division Of Neurosurgery Institute Of Neurological Sciences
関連論文
- A-26 新しいアプローチ(側頭下アプローチ)による海馬扁桃核摘出術
- Proteomic analysis of two types of exosomes in human whole saliva
- 正中部椎骨動脈解離性動脈瘤に対するbilateral transcondylar approach
- Proteomic Analysis of Two Types of Exosomes in Human Whole Saliva
- Co-localization of Human Growth Hormone and Human Prolactin in Hormonally Pure Human Growth Hormone-producing Pituitary Adenomas
- IB-O11 ヒトプロラクチン産生下垂体腺腫におけるレクチン組織細胞化学的検討
- 家族内に発生した Currarino 三徴の3症例
- 内視鏡下経鼻孔的下垂体手術
- Expression analysis of activin receptor interacting protein (ARIP) in Xenopus
- Cloning and characterization of Xenopus Activin receptor interacting protein(xARIP)(Developmental Biology)(Proceeding of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
- Pancreatic stellate cells express Toll-like receptors
- Magnetic Resonance Imaging in Kainic Acid-induced Limbic Seizure Status in Cats
- Retrolabyrinthine Presigmoid Transpetrosal Approach for Selective Subtemporal Amygdalohippocampectomy
- Salicylic Acid Carboxyl Methyltransferase Induced in Hairy Root Cultures of Atropa belladonna after Treatment with Exogeneously Added Salicylic Acid
- Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis
- Cell-surface arylsulfatase A and B on sinusoidal endothelial cells, hepatocytes, and Kupffer cells in mammalian livers
- Regression of Gastric Mucosa-Associated Lymphoid Tissue Lymphoma with Reduced Telomerase Activity after Eradication of Helicobacter pylori
- Ameliorated Outcome of Subarachnoid Hemorrhage Patients Treated with Reduced Form Glutathione
- P3-27 Localization of NBC-1 isoforms in rat and human kidneys
- MS2-4 Morphometrical evaluation of androgen action in testis and prostate
- Desmoplastic malignant mesothelioma : two cases and a literature review
- Immunohistochemical Localization of β-1, 4-Galactosyltransferase in Human Pancreatic Tissues
- Chordoma in the Sella Turcica
- Pulmonary pleomorphic carcinoma producing hCG
- Poorly Differentiated Adenocarcinoma with Signet-Ring Cell Carcinoma in a Hyperplastic Polyp of the Stomach : Report of a Case
- Exosome-Like Vesicles with Dipeptidyl Peptidase IV in Human Saliva(Biochemistry)
- Myosin Light Chain Phosphorylation is Correlated with Cold-Induced Changes in Platelet Shape
- Growth Inhibition of Helicobacter pylori by Monoclonal Antibody to Heat-Shock Protein 60
- Renal adenomatosis associated with carcinoma of the lower urinary tract : A case report with immunohistochemical study
- Leiomyosarcoma arising from soft tissue tumor of the mediastinum
- Malignant mesothelioma of the pericardium : Case reports and immunohistochemical studies including Ki-67 expression
- Synovial sarcoma arising from the pleura : a case report with ultrastructural and immunohistological studies
- Changes in AlPase Activity of Rabbit Articular Cartilages Associated with Aging and Joint Contracture
- Malignant mesothelioma of the peritoneum : case reports and immunohistochemical findings including Ki-67 expression
- Responses of Transformed Roots of Atropa Belladonna to Treatment with Salicylic Acid and other Phenolic Compounds
- Responses of Transformed Root Culture of Atropa belladonna to Salicylic Acid Stress
- Detection of Disialoganglioside in Rat Cerebellar Cortex by Light and Electron Microscopy
- P3-31 Distribution of the Long Form of Type XII Collagen during Chicken Corneal Formation
- Binding of Griffonia simplicifolia I-B_4 Lectin in the Substantia Gelatinosa of the Rat Spinal Cord
- P-47 Binding of Griffonia simplicifolia I-B_4 lectin in the substantia gelatinosa of rat spinal cord.
- Changes in HRP penetration into the articular cartilage of the experimentally contracted joint.
- The demonstration of the intracytoplasmic lectin binding sites in the granulocytes by means of ultracryotomy.
- Subcellular Localization of Galactosyltransferase Associated with Tumors in Endometrial and Ovarian Cancer Cells
- GLUT1 Glucose Transporter in the Lactating Mammary Gland in the Rat
- -651C/T promoter polymorphism in the CD14 gene is associated with severity of acute pancreatitis in Japan
- Effect of probiotic bacterial strains of Lactobacillus, Bifidobacterium, and Enterococcus on enteroaggregative Escherichia coli
- O-GlcNAc modification of nucleocytoplasmic proteins and diabetes
- Elevated Post-Translational Modification of Proteins by O-Linked N-Acetylglucosamine in Various Tissues of Diabetic Goto-Kakizaki Rats Accompanied by Diabetic Complications
- P-36-A Diabetic keratopathy and O-GlcNAc transferase in corneas of diabetic Goto-Kakizaki rat(THE JOINT MEETING OF THE 44TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY AND THE 35TH ANNUAL MEETING OF THE CLINICAL ELECTRON MICROS
- Phenotypic Alteration of Carbohydrate Antigens in Gynecological Malignancy
- Lectin-binding Patterns of the Normal and Malignant Endometrium.
- 29-II-07 Effects of steroid on the immunohistochemical expression of activated eosinophil cationic protein(THE JOINT MEETING OF THE 44TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY AND THE 35TH ANNUAL MEETING OF THE CLINICAL EL
- Importance of Carbohydrates and Platelets in the Early Events of Cancer Metastasis (Recent Progresses in Carbohydrate Histochemistry)
- Bortezomib potentially inhibits cellular growth of vascular endothelial cells through suppression of G2/M transition
- Changes in Lectin-binding Patterns of the Rat Gastric Mucosa Induced by Stress Ulcer
- Changes in Lectin Binding Patterns of Human Pulmonary Tissues in Association with Congenital Heart Diseases
- Thymic Carcinoma with a Large Cystic Lesion
- Localized pleural malignant mesothelioma
- Prognostic Significance Of Persistent Mediastinal Metastasis Following Induction Therapy In Large (>or=2cm) N2 or N3 Non-Small Cell Lung Cancer
- B-18 Histochemical Detection of Various Gangliosides in Rat Cerebellar Cortex
- Distribution of glycoconjugates in the colon carcinoma cells during the process of liver metastasis
- DBA-staining Pattern of Stimulated Human Gastric Parietal Cells : A Microspectrophotometric Study
- Light and Electron Microscopic Study of Lectin Binding Sites in Human Esophageal Epithelia
- Anaplastic large-cell lymphoma (Ki-1 lymphoma) : ultrastructural and immunohistochemical studies
- Case of primary malignant hemangiopericytoma of the heart expressing basement membrane-degradable enzymes
- Expression of Hex homeobox gene during skin development : Increase in epidermal cell proliferation by transfecting the Hex to the dermis
- Expression of matrix metalloproteinases, tissue inhibitors of metalloproteinase, collagens, and Ki67 antigen in pleural malignant mesothelioma : an immunohistochemical and electron microscopic study
- Pulmonary dirofilariasis : clinicopathological study
- Spiral artery of placenta : development and pathology-immunohistochemical, microscopical, and electron-microscopic study
- Increased exocytosis of secretory granules in contrast to reduced serum hormone levels in pituitary adenomas of humans and rats treated with dopamine agonist
- AN ELECTRON MICROSCOPIC STUDY ON THE HORSERADISH PEROXIDASE-LABELED NEURON IN THE EPILEPTIC FOCUS
- P-57 Immunohistochemical study on cellular co-localization of estrogen and progesterone receptors, HSP90, and pS2 in breast cancer tissues
- Multivariate Analysis of Patients with Head Injury Using Quantification Theory Type II : With Special Reference to Prediction of Patient Outcome
- Effects of Bromocriptine and Radiation on the Size and Activity of Estrogen-induced Rat Prolactinoms
- Effects of TRH or CB-154 on Functional Pituitary Adenoma Cells in Culture Revealed by Their Ultrastructural Study Using Cationized Ferritin
- USE OF FLUORESCEIN-PHALLOIDIN AND DAPI AS A COUNTERSTAIN FOR IMMUNOFLUORESCENCE MICROSCOPIC STUDIES WITH SEMITHIN FROZEN SECTIONS
- Identification and Properties of the Glucose Transporter of Human Erythrocytes(MEMBRANE PROTEINS AND TRANSPORT-II)
- Intrinsic Ureteric Involvement by Endometriosis : A Case Report
- Post-Isolation Inducible Nitric Oxide Synthase Gene Expression Due to Collagenase Buffer Perfusion and Characterization of the Gene
- Basic problems of digital image processing with personal computers
- P-58 Changes in expression of androgen receptor localized in spermatogonia in the cycle of the seminiferous epithelium: immunohistochemical, semi-quantitative study using the whole-mount method
- A Case Report : Rare Case of Primary Transitional Cell Carcinoma of the Fallopian Tube
- Immunohistochemical analyses of E-cadherin, β-catenin, CD44s, and CD44v6 expressions, and Ki-67 labeling index in intraductal papillary mucinous neoplasms of the pancreas and associated invasive carcinomas
- Immunohistochemical Localization of β-1, 4-Galactosyltransferase in Human Colonic Tissues
- B-1 Changes in Griffonia simplicifolia agglutinin- II and peanut agglutinin binding pattern in cell surface of mouse spermatogenic cells during postnatal development
- B-1 Changes in Griffonia simplicifolia agglutinin-II and peanut agglutinin binding pattern in cell surface of mouse spermatogenic cells during postnatal development
- Scanning Electron Microscope Study of Metacercarial Excystation of the Lung Fluke, Paragonimus Miyazakii
- SUGAR RESIDUES ON THE CELL SURFACE OF THE DISSOCIATED MOUSE KIDNEY TUBULE CELLS BY MEANS OF FERRITIN-LABELED LECTINS
- Comparison and Joint Use of the Peroxidase- and Ferritin-Labeling Methods on the Cell Surface Membranes (Symposium on the Enzyme-labeled Anitibody Method)
- Distribution of O-GlcNAc Transferase in the Rat Pancreas
- P-48 Glucose-induced Changes in O-GlcNAc Transferase Expression and Localization in Rat Aortic Smooth Muscle Cell
- Lectin Histochemical Study of Squamous Carcinoma in the Head and Neck Region
- Mg^-ATPASE ACTIVITY DURING ENDOCYTOSIS OF CATIONIZED FERRITIN IN MOUSE MACROPHAGES : A DOUBLE LABELING STUDY
- THE ENDOCYTOSIS AND THE INTRACELLULAR FATE OF CATIONIZED FERRITIN IN MONKEY MACROPHAGES
- Distribution of the Negative Charge on the Dissociated Thyroid Follicle Cell Surface
- Experimental Comparison of Flat-panel Detector Performance for Direct and Indirect Systems
- O-GlcNAc Transferase in Pancreas of Rats : Elevated expression of O-GlcNAc Transferase with Streptozotocin-induced Diabetes
- Choroid Plexus Papilloma Presenting With Cerebrospinal Fluid Rhinorrhea and Otorrhea : Case Report
- Gliosarcoma Associated With a Huge Cyst
- 慢性副鼻腔炎に合併した脳膿瘍例