IMMUNOHISTOLOGICAL STUDY OF ISOANTIGENS, CAR CINOEMBRYONlC ANTIGEN AND HUMAN CHORIONIC GONADOTROPlN IN ADENOCARClNOMAS OF THE UTERUS

元データ 1984-03-01 社団法人日本産科婦人科学会

概要

Isoantigens, carcinoembryonic antigen (CEA) and human chorionic gonadotropin (hCG) were simultaneously studied by immunohistology in the cervical and endometrial adenocarcinomas. Isoantigen loss was observed in all adenocarcinoma in situ (AIS) of the uterus. However, they appeared again in some tumor cells in 8 of 23 cervical and 4 of 41 endometrial adenocarcinomas. CEA was positive in I of 4 AIS and 22 of 23 adenocarcinomas of the cervix. It was distributed continuously in the apical portion and/or in the whole cytoplasm of tumor cells. On the other hand, CEA was positive only in 16 of 41 endometrial adenocarcinomas. It was strongly positive in the squamous elements, but weakly and sparsely in the apical portion and/or in the cytoplasm of some isolated glandular cells which occasionally showed a tendency to squamous differentiation. The majority of neoplastic glands, however, were negative for CEA. HCG was positive in I of 23 cervical and 3 of 41 endometrial adenocarcinomas. Two or 3 antigens were found concomitantly in some tumors, but localized differently from each other. It was concluded from the present study that the simultaneous examination of multiple antigens may be useful for characterization of adenocarcinomas of the uterus.

著者

INOUE Masaki Department of Obstetrics and Gynecology, Osaka University Medical School
SAITO Junko Department of Obstetrics and Gynecology, Osaka University Medical School
UEDA Gaiko Department of Obstetrics and Gynecology, Osaka University Medical School
TANAKA Yoshiaki Department of Medicinal Chemistry, Center for Frontier Research in Medicinal Science, Kyoto Pharmace
Ueda Gaiko Department Of Obstetrics And Gynecology Osaka University Medical School
Saito Junko Department Of Obstetrics And Gynecology Osaka University Medical School
Saito Junko Department Of Biology Faculty Of Education Yamanashi University
Inoue Masaki Department Of Obstetrics And Gynecology Osaka University Medical School
Inoue Masaki Department Of Gynecology And Obstetrics Kanazawa University School Of Medicine
YAMASAKI Masato Departments of Anatomy, Osaka City University Medical School
HIRAMATSU Keizo Department of Obstetrics and Gynecology, Osaka University Medical School
KURACHI Keiichi Department of Obstetrics and Gynecology, Osaka University Medical School
Tanaka Yoshiaki Department Of Obstetrics And Gynecology Osaka University Medical School
Yamasaki Masato Department Of Obstetrics And Gynecology Osaka University Medical School
Yamasaki Masato Department Obstetrics And Gynecology Osaka Rosai Hospital
Ueda Gaiko Department Of Obstetrics And Gynecology Okayama University Medical School
Kurachi Keiichi Department Of Obstetrics And Gynecology Osaka University Medical School
Kurachi Keiichi Department Of Obstetrics & Gynecology Osaka Medical School
INOUE Yoshinosuke Department of Obstetrics and Gynecology, Osaka University Medical School
NISHlNO Teruyo Department of Obstetrics and Gynecology, Osaka University Medical School
Hiramatsu Keizo Department Of Obstetrics And Gynecology Osaka University Medical School
Inoue Yoshinosuke Department Of Obstetrics And Gynecology Osaka University Medical School
Nishino Teruyo Department Of Obstetrics And Gynecology Osaka University Medical School
Inoue Masaki Department Of Architecture And Architectural Engineering Kyoto University
Tanaka Yoshiaki Department Of Gastroenterology Internal Medicine Kitasato University East Hospital
Tanaka Yoshiaki Department Bf Physics Faculty Of Science And Engineering Ritsumeikan University
TANAKA Yoshiaki Department of Obstetrics and Gynecology,Osaka University Medical School
Yamasaki Masato Department of Obstetrics and Gynecology,Osaka University Medical School
KURACHI KEIICHI Department of Gynecology and Obstetrics, Osaka University, Medical School

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