Monitoring the Progression of the Atrial Electrical Remodeling in Patients With Paroxysmal Atrial Fibrillation : Analysis of the f-f Interval During Ambulatory ECG Monitoring
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概要
- 論文の詳細を見る
It is important to clarify how electrical remodeling develops in clinical cases of paroxysmal atrial fibrillation (PAF), because it has been suggested that this electrophysiological phenomenon promotes an increase in the frequency of PAF. In the present study, the f-f interval during PAF was analyzed from the ambulatory ECG recordings of 21 patients with PAF (total PAF duration>2/24h with normal atrial size) to monitor the atrial electrophysiological changes. The patients were clinically followed-up for 6 months without any antiarrhythmic drugs. Before and after the follow-up period 24-h Holter monitoring was carried out and the duration of both the PAF and the f-f intervals during the PAF episode were evaluated. In selected cases, the atrial effective refractory period (ERP) was evaluated in an electrophysiologic study before and after the follow-up period. The total PAF duration was prolonged from 187±50 to 223±79 min (p=0.034) and the f-f interval was shortened from 0.14±0.03 to 0.12±0.02 ms (p=0.003). There was an inverse relationship between the changes in total PAF duration and f-f interval (p=0.027). The ERP was shortened from 214±15 to 194±5 ms (n=5, p=0.025) and there was a direct correlation between the changes in ERP and f-f interval (p=0.048). In clinical cases, the prolongation of the PAF was related to the shortening of the f-f interval during the PAF episodes and to the shortening of the atrial ERP. Electrical remodeling plays a role in promoting the development of the atrial fibrillation in patients with PAF.
- 社団法人日本循環器学会の論文
- 2003-01-20
著者
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YUMOTO Yoshihiro
Department of Cardio-Angiology, Kitasato University School of Medicine
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Izumi Tohru
Department Of Cardio-angiology Kitasato University School Of Medicine
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Wakisaka Yuko
Department of Adult Congenital Heart Disease, Chiba Cardiovascular Center
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NIWANO Shinichi
Department of Cardio-Angiology, Kitasato University School of Medicine
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NIWANO Hiroe
Department of Cardio-Angiology, Kitasato University School of Medicine
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Izumi Tohru
北里大学 医学部循環器内科
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SAITO Junko
Department of Obstetrics and Gynecology, Osaka University Medical School
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HARA Hideyuki
Department of Precision Science and Technology, Graduate School of Engineering, University of Osaka
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Kojima Jisho
Department of Cardio-angiology, Kitasato University School of Medicine
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Nakano Hironari
Department Of Cardio-angiology Kitasato University School Of Medicine
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Niwano Hiroe
Department Of Cardio-angiology Kitasato University School Of Medicine
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Kojima Jisho
北里大学 医学部循環器内科学
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Kojima Jisho
Department Of Cardio-angiology Kitasato University School Of Medicine
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Niwano Shinichi
Department Of Cardio-angiology Kitasato University School Of Medicine
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Niwano Shinichi
日本不整脈学会
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Inuo Kimiatsu
Department of internal Medicine,Kitasato University School of Medicine
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Yumoto Yoshihiro
北里大学 医学部循環器内科学
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Yumoto Yoshihiro
Department Of Cardio-angiology Kitasato University
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Wakisaka Yuko
千葉県循環器病センター 成人先天性疾患診療部
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Miwano Shinichi
北里大学
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Kojima Jisyo
Department Of Internal Medicine Kitasato University School Of Medicine
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Inuo Kimiatsu
北里大学 内科学
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Inuo Kimiatsu
Department Of Internal Medicine Kitasato University School Of Medicine
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Wakisaka Yuko
Department Of Pediatrics National Cardiovascular Center
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Saitou Junko
Department Of Internal Medicine Kitasato University School Of Medicine
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Saito Junko
Department Of Biology Faculty Of Education Yamanashi University
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Hara Hideyuki
Department Of Internal Medicine
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Hara Hideyuki
Department Of Internal Medicine Kitasato University School Of Medicine
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Niwano Shinichi
北里大学 医学部循環器内科学
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Niwano Shinichi
Department Of Cardio-angiology Kitasato University
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Izumi Tohru
Department Of Cardio-angiology Kitasato University School Of Medcine
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Hara Hideyuki
北里大学 医学部循環器内科学
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Hara Hideyuki
Department Of Electro Photo Optics Faculty Of Engineering Tokai University
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Izumi Tohru
Department Of Internal Medicine And Cardiology And Gene Genetcs Kitasato University School Of Medici
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Kojima Jisho
Department Of Internal Medicine Kitasato University School Of Medicine
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Izumi Tohru
Department Of Angio-cardiology Kitasato University School Of Medicine
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NIWANO Shinichi
Department of Cardio-andiology, Kitasato University School of Medicine
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Niwano Shinichi
Department of Angio-Cardiology, Kitasato University School of Medicine
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