気管内吸引カテーテル用消毒液の細菌汚染と消毒剤の殺菌効果

概要

論文の詳細を見る
Microbial contamination of 0.025% benzalkonium chloride (BAC), in which the tracheal suction catheter was soaked, was investigated. Six strains of Pseudomonas cepacia were isolated from 30 samples of 0.025% BAC which were used for 24h. The bactericidal activity of BAC and povidone-iodine (PVP-I) against clinical isolates of P.cepacia was evaluated by logarithmic reduction factors (LRFs)' Two strains of P.cepacia isolated from the disinfectant were resistant to BAC, and the LRFs of 0.025% BAC for these strains after 10min exposure were 0 and 0.12, respectively. The LRFs of 0.025% and 0.05% BAC for five strains of P.cepacia isolated from clinical specimens after I min exposure were less than 0.94 and 2.09, respectively. On the other hand, 0.1% BAC and 0.2% PVP-I showed antimicrobial activities against P.cepacia isolates tested, and the LRFs after 1 min exposure were more than 3 or 4. The LRFs of 0.025% BAC for P.cepacia were not significantly elevated by the presence of 10^v/_v% ethanol. These findings suggest that 0.1% BAC and 0.2% PVP-I are suitable for the disinfection of tracheal suction catheters.
日本医療薬学会の論文
1994-02-20