Lethal Activity of a Trehalase Inhibitor, Validoxylamine A, and its Influence on the Blood Sugar Level in Bombyx mori(Lepidoptera:Bombycidae)

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概要

• 論文の詳細を見る

• A trehalase inhibitor, validoxylamine A (VAA), gave a lethal effect in Bombyx mori larvae. Overall activities were reduced soon after injection of VAA at the 2nd day of the last instar larva. However, the lethal effect was found at the later stages. NMR analysis showed that trehalose was the main blood sugar and its level was strongly enhanced by the VAA injection. It was supposed that utilization of the energy source was prevented due to the trehalase inhibition, and consequently the overall activities were reduced. But, how the trehalase inhibition caused the lethal effect in the later stages remained unclear.

• 日本応用動物昆虫学会の論文
• 1993-08-25

著者

• Takeda Satoshi

  Department Of Insect Physiology And Behavior National Institute Of Sericultural And Entomological Sc

• Takeda Satoshi

  Department Of Emergency Medicine Jikei University School Of Medicine

• TAKAHASHI Masakazu

  Department of Pathology, Sasaki Institute

• NISHINA Masami

  Department of Medical Zoology, Saitama Medical School

• MATSUSHITA Kazuhiro

  Department of Medical Zoology, Saitama Medical School

• KONO Yoshiaki

  Department of Medical Entomology, National Institute of Infectious Diseases

• HORI Eitaro

  Department of Medical Zoology,Saitama Medical School

• KAMEDA Yukihiko

  Hokuriku University, School of Pharmacy

• Hori Eitaro

  Department Of Medical Zoology Saitama Medical School

• Kono Y

  Mitsubishi Heavy Industries Ltd. Kobe Shipyard & Machinery Works

• Takahashi M

  Kubota Corp Ibaraki Jpn

• Kono Y

  Graduate School Of Life And Environmental Sciences University Of Tsukuba

• Nishina Masami

  Department Of Immunology Saitama Medical School

• Takahashi Masakazu

  Department Of Microbiology Niigata College Of Pharmacy

• Matsushita Kazuhiro

  Laboratory Of Applied Entomology And Zoology Institute Of Agriculture And Forestry University Of Tsu

• KAMEDA Yukihiko

  School of Pharmacy, Hokuriku University

• MATSUSHITA Kazuhiro

  JEOL Ltd.

• Kameda Yukihiko

  School Of Pharmacy Hokuriku University

• Kono Yoshiaki

  Department Of Educational Psychology Tokyo Gakugei University

• Takahashi Masakazu

  Department Of Food Science And Technology Faculty Of Agriculture Kyoto University

• Takahashi Masakazu

  Department Of Bioscience Faculty Of Biotechnology Fukui Prefectural University

• Takeda Satoshi

  Department of Electrical and Electronic Engineering, Shizuoka University, 3-5-1 Johoku, Hamamatsu 432-8651, Japan

• MATSUSHITA Kazuhiro

  Laboratory of Applied Entomology and Zoology, Institute of Agriculture and Forestry, University of Tsukuba

• Takeda Satoshi

  Department of Chemistry, Faculty of Science, Hokkaido University

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