Sebaceous Gland Metaplasia in a Mammary Fibroadenoma Developing in a Female Donryu Rat
スポンサーリンク
概要
- 論文の詳細を見る
A mammary fibroadenoma with prominent sebaceous gland-like structures in a female Donryu rat aged 67 weeks was immunohistochemically investigated. The tumor demonstrated a mixture of both epithelial and connective tissue components, the former having both single- and multi-layered patterns. Characteristic sebaceous gland-like structures were apparent in connection with multi-layered epithelium. Area of single-layered epithelium comprised well-differentiated myoepithelial cells positive for alpha-smooth muscle actin (alpha-SMA), similar to mammary ducts. In contrast, many epithelial cells on the basal sides of multi-layers were negative for alpha-SMA, but positive for cytokeratin 14 (CK14), suggesting pluripotency. From these results, we diagnosed this case as a mammary fibroadenoma with sebaceous gland metaplasia.
- 日本毒性病理学会の論文
- 2002-03-25
著者
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MAEKAWA Akihiko
Chemical Management Center, National Institute of Technology and Evaluation
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Yoshida Midori
National Institute of Health Sciences
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MAEKAWA AKIHIKO
Department of Pathology, Sasaki Institute
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YOSHIDA Midori
Department of Pathology, Sasaki Institute
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TAKAHASHI Masakazu
Department of Pathology, Sasaki Institute
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Yoshida Midori
Div. Of Pathology National Inst. Of Health Sciences
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Yoshida Midori
Department Of Pathology Sasaki Institute
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SHIMOMOTO Takasumi
Department of Pathology, Sasaki Institute
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Shimomoto T
Department Of Pathology Sasaki Institute
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Maekawa A
Chemical Management Center National Inst. Of Technol. And Evaluation
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Maekawa Akihiko
Chemical Management Center National Institute Of Technology And Evaluation
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Maekawa Akihiko
Department Of Pathology Nagoya City University Medical School
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Maekawa Akihiko
Safety Assessment Division Chemical Management Center National Institute Of Technology And Evaluatio
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Takahashi Masakazu
Division Of Pathology National Institute Of Health Sciences
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Takahashi Masakazu
Department Of Microbiology Niigata College Of Pharmacy
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Shimomoto Takasumi
Department Of Pathology Sasaki Institute
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Takahashi Miwa
National Institute of Health Sciences
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Takahashi Masakazu
Department Of Pathology Sasaki Institute Sasaki Foundation
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Takahashi Masakazu
National Institute Of Health Sciences
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Takahashi Masakazu
Department Of Food Science And Technology Faculty Of Agriculture Kyoto University
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Takahashi Masakazu
Department Of Bioscience Faculty Of Biotechnology Fukui Prefectural University
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SHIMOMOTO Takasumi
Department of Molecular Pathology, Nara Medical University
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