<原著>開胸犬における左心室外周の100%酸素吸入による縮少

概要

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This study is performed to clarify whether or not oxygen breathing causes a reduction in the left ventricular size and reduces myocardial oxygen demand and thus causes a favorable effect on the ischemic myocardium. In 11 open-chest dogs, Mercury-in-Silastic gauges were sutured on the left ventricular wall to measure the segment length of the left ventricle while breathing room air and 100% oxygen. Segment lengths at the beginning of ventricular ejection (L1), end of ejection (L2), early diastole (L3) and end of diastole (L4) were significantly reduced from 24.87 to 24.40 mm (L1), from 26.83 to 26.15mm (L2), from 17.53 to 17.39 mm (L3) and from 17.69 to 17.46mm (L4) by oxygen breathing, respectively. Systolic shortenings of the segments calculated as a difference between L1 and L2,L3 or L4 were also significantly decreased by oxygen breathing. These changes were reversed when oxygen breathing was ceased. It was suggested that the reduction in the segment length of the left ventricle by oxygen breathing adds a beneficial effect, although it is small in quantity, on the ischemic myocardium by reducing myocardial oxygen demand.
近畿大学の論文
1978-12-25