Two Cases of Multiple Carcinoid Tumors and Gastric Enterochromaffin-like Cell Hyperplasia, Dysplasia and Neoplasia in Type A Gastritis

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概要

• 論文の詳細を見る

• We describe two cases of multiple carcinoids and hyperplasia, dysplasia and neoplasia of enterochromaffin-like (ECL) cells associated with atrophic gastritis type A in the stomach. Multiple polypoid lesions measuring 1 cm showed upper gastroendoscopic features. They were all found in the upper body of the stomach. All polypoid lesions with carcinoid foci were observed from the deeper layers of the propria mucosa to the submucosa and were surrounded by ECL cells. In one case, the serum gastrin level which was as high as 1700 pg/mi, returned to normal range (17 pg/ml) after gastrectomy. It is suggested that longstanding hypergastrinemia may have played a causative role in the development of multiple gastric carcinoid tumors. A total gastrectomy was considered essential for treatment of aggressive multiple carcinoid tumors with hypergastrinemia.

• 長崎大学の論文

著者

• Nagayasu Takeshi

  長崎大学 大学院腫瘍外科

• NAKAYAMA Toshiyuki

  Department of Pathology, Atomic Disease Institute, Nagasaki University School of Medicine

• Sekine I

  Tissue And Histopathology Section Division Of Scientific Data Registry Atomic Bomb Disease Institute

• Sekine Ichiro

  長崎大学 医歯薬学総合研究科腫瘍診断病理学

• Nakashima Masahiro

  Department Of Internal Medicine I National Defense Medical College

• FUKUDA Eiichiro

  Department of Molecular Pathology

• Gabit Alipov

  Tissue and Histopathology Section, Division of Scientific Date Registry, Atomic Bomb Disease Institu

• Nakashima Masahiko

  Department of Molecular Pathology, Atomic Bomb Disease Institute, Nagasaki University School of Medi

• Nakashima Masahiko

  Tissue And Histopathology Section Division Of Scientific Data Registry Atomic Bomb Disease Institute

• Nakashima Masahiro

  長崎大医歯薬学総合研究科原研 病態分子解析

• Nakashima Masahiro

  Tissue And Histopathology Section Division Of Scientific Data Registry Nagasaki University Graduate

• Nakayama Toshiyuki

  Division Of Tumor And Diagnostic Pathology Atomic Bomb Disease Institute Nagasaki University Graduat

• Nakayama Toshiyuki

  Department Of Hematology Kouseiren Tsurumi Hospital

• Sekine Ichiro

  長崎大学医学部附属原爆後障害医療研究施設 生体材料保存室

• Niino Daisuke

  Department Of Pathology School Of Medicine Kurume University

• Sekine Ichiro

  Div. Of Tumor And Diagnostic Pathology Atomic Bomb Disease Inst. Nagasaki Univ. Graduate School Of B

• Sekine Ichiro

  Department Of Pathology Atomic Disease Institute Nagasaki University School Of Medicine

• Nakayama Toshiyuki

  Division Of Surgical Oncology Nagasaki University Graduate School Of Biomedical Sciences

• Sekine Ichiro

  Division Of Tumor And Diagnostic Pathology Atomic Disease Institute Nagasaki University Graduate Sch

• Fukuda Eiichiro

  Department Of Internal Medicine Nagasaki National Medical Center

• Sekine Ichiro

  Department Of Molecular Pathology Atomic Bomb Disease Institute Nagaski University School Of Medicin

• Alipov Gabit

  Tissue and Histopathology Section, Division of Scientific Date Registry, Atomic Bomb Disease Institute, Nagasaki University School of Medicine

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