Serum Level of Hyaluronic Acid Does not Correlate with Changes of Hepatic Volume after Portal Vein Embolization
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概要
- 論文の詳細を見る
The serum hyaluronic acid (HA) levels are associated with liver regeneration after hepatectomy. In the present study, the HA concentrations were examined to evaluate the relationship with changes of hepatic volume after right portal vein embolization (PVE). The HA level of serum samples from 10 patients who underwent PVE before hepatectomy of the right lobe was measured, and the results were compared to the changed volume of embolized right lobe and unembolized left lobe of the liver. The mean serum HA level in patients with chronic viral liver disease (CVLD) (202+/-118 ng/ml) was significantly greater than in those without CVLD (70+/-24 ng/ml) (p<0.05). The volume of embolized liver decreased 72+/-96 CM3 (-8.9+/-5.5 %), while the volume of unembolized liver increased 106+/-67 CM3 (+8.9+/-5.5 %) 2 weeks after PVE. HA concentrations after 2 weeks of PVE (296+/-216 ng/ml) tended to be greater than that before PVE (134+/-108 ng/ml) but not statistically significant (p=0.105). There were no correlations between serum HA levels before PVE and the changes of hepatic volume in embolized and unembolized lobe after PVE. Our results indicate that the measurement of HA level is not useful for predicting the effect of PVE.
- 長崎大学の論文
著者
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Nagayasu Takeshi
長崎大学 大学院腫瘍外科
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Yamaguchi H
Division Of Surgical Oncology Department Of Translational Medical Sciences Nagasaki University Gradu
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Yamaguchi Hiroyuki
長崎大学 医歯薬総研究腫瘍外科学
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Tamaru Naoe
Department Of Pathology Nagasaki University Hospital
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AYABE HIROYOSHI
First Department of Surgery, Nagasaki University School of Medicine
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NANASHIMA Atsushi
The First Department of Surgery, Nagasaki University School of Medicine
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Nakashima Atsushi
The First Department of Surgery, Nagasaki University of Medicine
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Shindo Hisakazu
Division Of Surgical Oncology Department Of Surgery Nagasaki University Graduate School Of Biomedica
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Nakashima Atsushi
Division Of Surgical Oncology Department Of Translational Medical Sciences Nagasaki University Gradu
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Yano Hiroshi
Division Of Surgical Oncology Department Of Surgery Nagasaki University Graduate School Of Biomedica
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Shibasaki Shinichi
Division Of Surgical Oncology Department Of Translational Medical Sciences Nagasaki University Gradu
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Ayabe Hiroyoshi
First Department Of Surgery Nagasaki University School Of Medicine
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Ayabe Hiroyoshi
The First Department Of Surgery Nagasaki University School Of Medicine
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Ayzbe Hiroyoshi
First Department Of Surgery Nagasaki University School Of Medicine
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Nakamura Akihiro
Division Of Surgical Oncology Nagasaki University Graduate School Of Biomedical Sciences
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Nagayasu Takeshi
Division Of Surgical Oncology Department Of Surgery Nagasaki University Graduate School Of Biomedica
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Hidaka Shigekazu
Division Of Surgical Oncology Department Of Surgery Nagasaki University Graduate School Of Biomedica
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Yamaguchi Hiroyuki
First Department Of Surgery Nagasaki University School Of Medicine
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Ayabe Hiroyoshi
Department Of First Surgery Nagasaki University School Of Medicine
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Nagayasu Takeshi
Division Of Surgical Ontology Nagasaki University Graduate School Of Biomedical Sciences
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Yano Hiroshi
Division Of Surgical Oncology Department Of Surgery Nagasaki University Graduate School Of Biomedica
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Nagayasu Takeshi
長崎大学 大学院医歯薬学総合研究科腫瘍外科第1外科
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