Type of Operation does not Affect Survival after Non-curative Resection for Adenocarcinoma of the Rectum at or below the Peritoneal Reflection: a Multivariate Analysis

概要

論文の詳細を見る
Purpose. The purpose of this study was to determine whether the type of operation [sphincter-saving resection (SSR) or abdominoperineal resection (APR)] for primary adenocarcinoma of the rectum at or below the peritoneal reflection affects survival after non-curative surgery. Methods. This retrospective study included 42 patients who underwent non-curative surgery by the following two types of operation between 1989 and 1998: (1) SSR (n=19 patients) included low anterior resection with either double-stapling technique (n=16) or transanal coloanal anastomosis (n=3); (2) APR (n=23). 'Non-curative' resection implied 'Curability B' and 'Curability C' defined by the Japanese Classification of Colorectal Carcinoma. Outcome measure was diseasespecific survival. Univariate and multivariate Cox's regression analyses were used to evaluate data. Median follow-up was 17.2 months at study conclusion. Results. Disease-specific survival after non-curative surgery did not differ between the two types of operations. Multivariate analyses showed that the type of operation was not a significant independent variable in predicting disease-specific survival after surgery. One variable - 'Curability' - was significant predictor of outcome after surgery. Conclusions. The type of operation (SSR or APR) did not affect survival after non-curative resection for adenocarcinoma of the rectum at or below the peritoneal reflection.
長崎大学の論文