Microarray analysis of 6-mercaptopurine-induced-toxicity-related genes and microRNAs in the rat placenta
スポンサーリンク
概要
- 論文の詳細を見る
- 2013-02-01
著者
-
Yoshida Takemi
Department Of Biochemical Toxicology School Of Pharmaceutical Science Showa University
-
Ise Ryota
Department Of Biochemical Toxicology School Of Pharmacy Showa University
-
Horii Ikuo
Department Of Biochemical Toxicology School Of Pharmacy Showa University
-
Fukushima Tamio
Department Of Biochemical Toxicology School Of Pharmacy Showa University
-
Taki Kenji
Department Of Biochemical Toxicology School Of Pharmacy Showa University
-
FUKUSHIMA Tamio
Department of Biochemical Toxicology, School of Pharmaceutical Sciences, Showa University
関連論文
- Recreational drugs, 3,4-Methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxyamphetamine (MDA) and diphenylprolinol, inhibit neurite outgrowth in PC12 cells
- Salbutamol inhibits lipopolysaccharide-induced inflammatory responses in rat peritoneal macrophages
- A METHOD FOR ESTIMATION OF HEPATIC DRUG-METABOLIZING CAPACITY : DETERMINATION OF CONCENTRATION OF TRIMETHADIONE AND ITS METABOLITE IN HUMAN SERUM
- Toxicological assessment of a novel anti-tumor agent Capecitabine (Ro 09-1978, 5'-DFCR derivative : Species differences and improvement of intestinal toxicity
- Toxicological assessment of a novel anti-tumor agent Capecitabine (Ro 09-1978, 5'-DFCR derivative) : Toxicokinetics in monkeys, rats and mice
- Detection of Bisphenol-A in Dental Materials by Gas Chromatography-Mass Spectrometry
- Possible role of inflammatory cytokines in liver injury caused by cocaine (LIVER/DIGESTIVE SYSTEM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- ASSESSMENT OF QUANTITATIVE DUAL-PARAMETER FLOW CYTOMETRIC ANALYSIS FOR THE EVALUATION OF TESTICULAR TOXICITY USING CYCLOPHOSPHAMIDE -AND ETHINYLESTRADIOL- TREATED RATS
- FLOW CYTOMETRIC ANALYSIS FOR SPERM VIABILITY AND COUNTS IN RATS TREATED WITH TRIMETHYLPHOSPHATE OR PYRIDOXINE
- Flow cytometric analysis of sperm viability and number in the rats treated with Trimethylphosphate and Ornidazole.
- CHALLENGE TO IN VITRO ANTIGENICITY STUDY IN HUMAN LYMPHOCYTES : ESTABLISHMENT OF TEST SYSTEM USING HETEROGENEOUS PROTEINS AS ANTIGENS
- TISSUE- AND DOSE-DEPENDENT ALTERATION OF STRESS-INDUCIBLE PROTEINS BY β_2-ADRENOCEPTOR AGONIST, SALBUTAMOL, IN RATS
- QUANTITATIVE ESTIMATION OF MYOCARDIAL FIBROSIS BASED ON RECEPTOR OCCUPANCY FOR β_2-ADRENERGIC RECEPTOR AGONISTS IN RATS
- Establishment and Peculiarity of Ouabain-resistant THP-1 cells
- COMPARISON OF THE EFFECT OF AN EQUIMOLAR AND LOW DOSE OF FENITROTHION AND METHYLPARATHION ON THEIR OWN METABOLISM IN RAT LIVER
- ALTERATIONS OF HEPATIC MITOCHONDRIAL MONOAMINE OXIDASE ACTIVITY OF RATS DURING 2-ACETYLAMINOFLUORENE FEEDING
- Induction and Inhibition of Cytochrome P450 and Drug-Metabolizing Enzymes by Climbazole
- SEX-RELATED EFFECT OF HEMIN ON CYTOCHROME P450 AND DRUG-METABOLIZING ENZYMES IN RAT LIVER
- MALE FERTILITY IN RATS TREATED WITH ETRETINATE FOR 4 WEEKS (<SPECIAL ISSUE>TESTICULAR TOXICITY)
- INTEGRATED NMR-BASED METABONOMIC INVESTIGATION OF EARLY METABOLIC EFFECTS OF ETHYLENE GLYCOL MONOMETHYL ETHER (EGME) ON MALE REPRODUCTIVE ORGANS IN RATS
- EFFECT OF ETRETINATE (AROMATIC RETINOID) TREATMENT DURING GESTATION AND LACTATION PERIODS ON VIABILITY AND SOMATIC GROWTH IN F1 RATS
- EFFECT OF 1,25-DIHYDROXYVITAMIN D_3 ON THE FEMALE REPRODUCTIVE SYSTEM IN RATS
- Induction of oxidative stress responsive proteines by methyl methanesulfonate, which produces reproductive toxicity (DEVELOPMENT AND REPRODUCTION) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- TISSUE-DEPENDENT INDUCTION OF HEME OXYGENASE-1 AND METALLOTHIONEIN-1/2 BY METHYL METHANESULFONATE
- STUDIES ON THE MECHANISM OF INTERACTION BETWEEN METHAMPHETAMINE AND QUININE IN RATS
- Bisphenol-A contents in materials used in pediatric dentistry
- Regulation of ERK-Mediated Signal Transduction by p38 MAP Kinase in Human Monocytic THP-1 Cells
- INDUCTION OF HEPATIC CYP2B1/2 BY A TERATOGENIC COMPOUND cis-1-[-4-P-MENTHANE-8-YLOXY)PHENYL]PIPERADINE(YM9429)IN RATS
- Selective Inhibition of Chondrogenic Differentiation in Embryonic Cells by a Teratogenic Compound
- Possible Role of Glutathione Depletion in the Induction of Rate-Limiting Enzymes Involved in Heme Degradation and Polyamine Biosynthesis in the Liver of Rats
- Comparative Studies on the Inducing Effects of Cobalt Chloride and Co-Protoporphyrin on Hepatic Ornithine Decarboxylase and Heme Oxygenase in Rats
- DEPLETION OF HEPATIC GLUTATHIONE IS FOLLOWED BY THE INDUCTION OF HEME OXYGENASE AND CHANGES IN DRUG-METABOLIZING ENZYMES
- Relationship between Hepatic Glutathione Consumption and the Induction of Enzymes Involved in Polyamine Biosynthesis Evoked by Various Drugs and Chemicals (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology)
- EVALUATION OF THE INDUCTION OF HEPATIC DRUG-METABOLIZING ENZYMES IN THE RAT AND MOUSE TREATED WITH TEMAZEPAM USING TRIMETHADIONE AS THE INDICATOR
- RELATIONSHIP BETWEEN TRIMETHADIONE METABOLISM AND HEPATIC DRUG-OXIDIZING ENZYME ACTIVITIES IN DIFFERENT ANIMAL SPECIES
- STUDIES ON THE TRIMETHADIONE METABOLISM AS A TOOL FOR THE ASSESSMENT OF DRUG-METABOLIZING CAPACITY USING PLASMA AND URINE OF RATS PRETREATED WITH PHENOBARBITAL AND 3-METHYLCHOLANTHRENE
- DETERMINATION OF PLASMA TRIMETHADIONE AND ITS METABOLITE IN CARBON TETRACHLORIDE-INTOXICATED RATLIVER : A USEFUL TOOL FOR ESTIMATION OF HEPATIC DRUGMETABOLIZING CAPACITY
- SALIVA LEVELS OF TRIMETHADIONE AND ITS METABOLITE AS AN INDEX OF DRUG METABOLIZING ACTIVITY IN RATS
- "A-12 Investigation of SCID mice transferred with human lymphocytes (hu-PBL-SCID mice) for the evaluation of toxicity on human immune system. : Human immunoglobulin production in hu-PBL-SCID mice
- P-80 Comparative 4 AND 2 Weeka Oral Repeated Dosing Studies On Male Reproductive Organs in Rats Treated With 5-Fluorouracil.(Proceedings of the 27th Annual Meeting)
- COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : 18)COMPARATIVE 4 AND 2 WEEKS ORAL REPEATED DOSING STUDIES ON MALE REPRODUCTIVE ORGANS IN RATS TREATED WITH 5-FLUOROURACIL
- COMPARATIVE TOXICOLOGICAL ASSESSMENT OF A WATER-SOLUBLE AZOLE ADMINISTERED BOTH ORALLY AND BY INTRAVENOUS CONTINUOUS INFUSION IN CYNOMOLGUS MONKEYS
- INDUCTION OF HEME OXYGENASE AND INHIBITION OF δ-AMINOLEVULINIC ACID SYNTHETASE OF RAT LIVER BY THIOACETAMIDE AND THIOACETAMIDE-S-OXIDE
- TOXICOKINETICS:ITS SIGNIFICANCE AND PRACTICAL PROBLEMS
- SIMULTANEOUS INDUCTION OF ORNITHINE DECARBOXYLASE AND HEME OXYGENASE UNDER VARIOUS EXPERIMENTAL CONDITIONS
- EFFECTS OF DOXIFLURIDINE(DFUR)ON MOUSE THYMOCYTE DIFFERENTIATION
- Metallothionein Synthesis Induced by Interferon α/β in Mice of Various Zinc Status
- Metabolism of Ipecac Alkaloids Cephaeline and Emetine by Human Hepatic Microsomal Cytochrome P450s, and Their Inhibitory Effects on P450 Enzyme Activities
- Determination of muscimol and ibotenic acid in Amanita mushrooms by high-performance liquid chromatography and liquid chromatography-tandem mass spectrometry
- EFFECTS ON FETAL THYMOCYTE POPULATIONS AND POSTNATAL T-CELL-DEPENDENT IMMUNE FUNCTIONS AFTER MATERNAL EXPOSURE TO 5-FLUOROURACIL DURING PREGNANCY IN MICE
- Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans - toxicological implications
- POTENTIATION OF AFLATOXIN B_1 INDUCED HEPATOTOXICITY IN MALE WISTAR RATS WITH ETHANOL PRETREATMENT
- AN INDUCTION OF HEME OXYGENASE AND ITS POSSIBLE RELATION TO THE DECREASE OF CYTOCHROME P-450 CONTENT DURING LIVER REGENERATION
- ALTERATIONS OF DRUG AND HEME METABOLIZING ENZYMES DURING LIVER REGENERATION
- EFFECT OF HEAVY METALS ON SOME ENZYMES OF RAT LIVER AND FACTORS WHICH MODIFY THE METAL ACTIONS, ESPECIALLY OF CADMIUM
- Interleukin-1 Controls the Constitutive Expression of the Cyp7a1 Gene by Regulating the Expression of Cyp7a1 Transcriptional Regulators in the Mouse Liver
- The mechanism of induction of HO-1 gene transactivation by 4-HNE.(GENERAL SESSION BY POSTER PRESENTATION)(ACTIVE OXYGEN ETC)
- O-56 Involvement of aPKC in Oxidative Stress-induced Heme Oxygenase-1.(Proceedings of the 27th Annual Meeting)
- Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-1
- Report 3 : FUTURE PROSPECTS FOR TOXICOKINETICS : ITS ABILITY TO PREDICT DRUG ADVERSE EVENTS IN HUMANS (TOXICOKINETICS)
- COMPARATIVE IMMUNOTOXICITY ASSESSMENT OF N^4-TRIMETHOXYBENZOYL-5'-DEOXY-5-FLUOROCYTIDINE (RO 09-1390) AND 5'-DEOXY-5-FLUOROURIDINE (5'-DFUR) IN BDF1 MICE
- Detection of acetazolamide-induced increase in organ blood flow in rabbits by laser flowmetry
- ANALYSIS OF THE EXPRESSION OF HEME OXYGENASE-1 GENE IN HUMAN ALVEOLAR EPITHELIAL CELLS EXPOSED TO CIGARETTE SMOKE CONDENSATE
- Nrf2-DEPENDENT GENE EXPRESSIONS : A MOLECULAR TOXICOLOGICAL ASPECT
- Biological Surveillance and Defense Mechanism for Drug Toxicity and Its Breakdown(SYMPOSIUM 1 : MECHANISMS OF HEPATOTOXIC EFFECTS)
- 2B-22 Homologous passive cutaneous anaphylaxis test in mice
- Inhibitory effect of endothelin receptor antagonist on growth of 3T3-E1 osteoblastic cells in vitro.
- AROMATIC RETINOID RO 40-8757 REDUCES IMMUNOTOXICITIES OF CYCLOPHOSPHAMIDE AS REVEALED BY IMMUNOHISTOCHEMICAL STAINING OF LYMPHOID TISSUES AND GENERAL PATHOLOGIC EXAMINATIONS
- Investigation of in vitro antigenicity study by using dendritic cells induced from mouse bone marrow cells. Expression of cell surface markers by exposure to antigens.(GENERAL SESSION BY ORAL PRESENTATION)(IMMUNE AND ALLERGIC SYSTEM)
- ENDOCRINOLOGICAL ASSESSMENT OF TOXIC EFFECTS ON THE MALE REPRODUCTIVE SYSTEM IN RATS TREATED WITH 5-FLUOROURACIL FOR 2 OR 4 WEEKS
- O12-14 Significant endocrinological parameters for the assessment of male reproductive toxicity induced by 1, 3-Dinitrobenzene or Taxol
- Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans - toxicological implications
- TRIMETHADIONE AS A MODEL DRUG FOR THE EVALUATION OF HEPATIC DRUG-METABOLIZING CAPACITY IN NORMAL AND D-GALACTOSAMINE INTOXICATED RATS
- Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-1
- 6-Mercaptopurine-induced histopathological changes and xanthine oxidase expression in rat placenta
- PRODUCTION OF TOLERANCE TO FENITROTHION I N MALE RATS
- Possible Involvement of Transient Receptor Potential Channels in Electrophile-Induced Insulin Secretion from RINm5F Cells
- Involvement of Interleukin-1 in Lead Nitrate-Induced Hypercholesterolemia in Mice
- Early effects of 2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene on mitochondrial outer membrane enzyme activities of rat liver.
- Microarray analysis of 6-mercaptopurine-induced-toxicity-related genes and microRNAs in the rat placenta