Vertical Transmission to Embryo and Fetus in Maternal Infection with Rat Virus (RV)
スポンサーリンク
概要
- 論文の詳細を見る
The influence of maternal rat virus (RV) infection on rat embryogenesis and fetus was examined by viral reisolation, immunostaining and PCR analysis. Vertical transmission caused by the UT-1 strain of RV depended on the stage of gestation when maternal infection occurred. When females were infected at the pre-mating point, the number of fetuses was smaller than that normally obtained, possibly due to infection at the stage of the hatched blastocyst, but almost all of the fetuses obtained were free from infection and developed normally. The incidence of transplacental infection was the highest when pregnant females were infected in the middle of the gestation stage, and some of the fetuses died. In pregnant females which were infected late in the gestation stage, all fetuses developed normally. Some of them were infected transplacentally and harbored the infectious virus. Much attention should be paid to performing reliable rederivation of RV-infected rat colonies by hysterectomy and embryo transfer.
- 社団法人 日本実験動物学会の論文
著者
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SUGIYAMA Fumihiro
Laboratory Animal Research Center
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YAGAMI Ken-ichi
Laboratory Animal Research Center
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杉山 文博
Institute Of Basic Medical Sciences Laboratory Animal Resource Center University Of Tsukuba
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杉山 文博
久留米大学医学部附属動物実験センター
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Takakura A
Iclas Monitoring Center Central Institute For Experimental Animals
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Ueno Yutaka
Laboratory Animal Resource Center
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高倉 彰
財団法人実験動物中央研究所
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Takakura Akira
実験動物中央研究所 Iclasモニタリングセンター
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KAJIWARA Noriko
Laboratory Animal Research Center, University of Tsukuba
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TAKAHASHI Akio
Laboratory Animal Research Center, University of Tsukuba
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SUGIYAMA Yoshihiro
Laboratory Animal Research Center, University of Tsukuba
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Yagami Ken-ichi
Laboratory Animal Resource Center University Of Tsukuba
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Yagami Ken-ichi
Institute Of Basic Medical Sciences Laboratory Animal Resource Center University Of Tsukuba
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Sugiyama Fumihiro
Laboratory Animal Resource Center University Of Tsukuba
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Kajiwara Noriko
Lab. Animal Resource Center Univ. Of Tsukuba
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Sugiyama Yoshihiro
Laboratory Animal Research Center University Of Tsukuba
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Sugiyama Fumihiro
Laborarory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan
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Kajiwara Noriko
Laborarory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan
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Yagami Ken-ichi
Laborarory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan
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