“もやもや”病の術前,術後の経時的脳循環代謝の変化

概要

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The authors studied the sequential changes of cerebral blood flow and cerebral metabolism after surgical treatment in“moyamoya”disease. The CBF studies were made in 21 patients, 28 sites with“moyamoya”disease; ST·MC anastomoses combined with or without encephalo-myo-synangiosis (EMS) in 16 patients, 18 sites, and EMS only in 9 patients, 10 sites, The measurement of CBF were made by use of Argon and medical massspectrometry, according to the Fick's principle.<BR>CBF increased in 2 days after operation, followed low CBF values in a month later, But CBF met with good results at over 3 months after operation, not only in ST·MC anastomosis group, but also in EMS group. CMRO2 decreased in 2 days after operation in the patients with postoperative transient neurological deficits, then, increased to high values compared with preoperative values in accord with the disappearance of postoperative neurological deficits <BR>These CBF results supported that ST·MC anastomosis and EMS for“moyamoya”disease are effective.