悪性リンパ腫95例の臨床的検討 (三吉康郎教授開講20周年記念論文集)

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Statistical observation of 95 patients with malignant lymphoma of the head and neck region treated for over 20 years (1961-1980) has been made.Statistical details were as follows.1) They included 59 males and 36 females with a male to female ratio of 1.6. Age distribution was such that the highest incidence was in the 6th decade.2) Twenty-nine percent of all the cases had painless swelling of cervical lymphnodes, which was the most frequent clinical sign, but most of the patients with malignant lymphoma of palatine tonsils and extra-lymphatic organs were characterised by local symptoms.3) Waldeyer's ring involvement in which the tonsil was the most popular site was seen in 65 (68%) of the 95 patients. Involvement of the nose and paranasal sinuses was not uncommon (9.5%).4) Stage II with lymphatic organ involvement was the most frequent (52%), in contrast to diffuse distribution to extra-lymphatic organs.5) In the histopathological distribution, almost all the cases were non-Hodgkin's lymphomata (97%), of which 81 were reticulum cell sarcoma and 10, lymphosarcoma.6) Most of the patients were treated by telecobalt or Lineac irradiated on the primary site regardless of the clinical stage. Although combined chemotherapy including MOPP, VEMP, CVP and VP was introduced from 1971 onwards, there was no criteria for indication of these modes of therapy.7) The 5-year survival rate was 47.1% for stage I, 25% for II, 28.6% for III, 0% for IV. It was higher in lymphatic organs than in extra-lymphatic organs. There was no difference in prognosis between the treatment with or without chemotherapy.These results indicate that lymphography, Ga scintigraphy and X-ray examination must be performed routinely before treatment in order to determine the clinical stage correctly. Regional irradiation is effective for the loco-regional stage but not effective for stage II with diffuse spreading.
耳鼻咽喉科臨床学会の論文

悪性リンパ腫95例の臨床的検討 (三吉康郎教授開講20周年記念論文集)

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